Literature DB >> 11535721

Impact of whole-body 18F-FDG PET on staging and managing patients with breast cancer: the referring physician's perspective.

C S Yap1, M A Seltzer, C Schiepers, S S Gambhir, J Rao, M E Phelps, P E Valk, J Czernin.   

Abstract

UNLABELLED: FDG PET has emerged as an important clinical imaging modality for diagnosing and staging cancer. However, the impact of FDG PET on staging and managing patients with breast cancer from the referring physician's point of view is unknown.
METHODS: The referring physicians of 160 breast cancer patients received standardized questionnaires inquiring if and how PET findings altered their patient's stage and their clinical management decisions. Management changes were classified as intermodality if the change was from one modality to another (e.g., medical to surgical, surgical to radiation, medical to no treatment, and vice versa) or as intramodality if the change was within the same modality (e.g., altered medical or radiotherapy approach).
RESULTS: Fifty of the 160 surveys were completed (31% response rate). PET changed the clinical stage in 36% of patients (28% upstaged, 8% downstaged) and resulted in intermodality changes in 28% of patients and intramodality changes in 30% of patients.
CONCLUSION: The results of this prospective survey show that FDG PET has a major impact on the management of breast cancer patients, influencing both clinical stage and management in more than 30% of patients.

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Year:  2001        PMID: 11535721

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  19 in total

Review 1.  PET/CT and breast cancer.

Authors:  Barbara Zangheri; Cristina Messa; Maria Picchio; Luigi Gianolli; Claudio Landoni; Ferruccio Fazio
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-05-05       Impact factor: 9.236

2.  Tumour markers and FDG PET/CT for prediction of disease relapse in patients with breast cancer.

Authors:  Laura Evangelista; Zora Baretta; Lorenzo Vinante; Anna Rita Cervino; Michele Gregianin; Cristina Ghiotto; Giorgio Saladini; Guido Sotti
Journal:  Eur J Nucl Med Mol Imaging       Date:  2010-09-30       Impact factor: 9.236

3.  Oncologic positron emission tomography: a surgical perspective.

Authors:  Todd O Moore; Landis K Griffeth
Journal:  Proc (Bayl Univ Med Cent)       Date:  2003-01

Review 4.  Current and future use of positron emission tomography (PET) in breast cancer.

Authors:  David A Mankoff; William B Eubank
Journal:  J Mammary Gland Biol Neoplasia       Date:  2006-04       Impact factor: 2.673

5.  Significant clinical impact and prognostic stratification provided by FDG-PET in the staging of oesophageal cancer.

Authors:  Cuong P Duong; Helen Demitriou; Leann Weih; Anne Thompson; David Williams; Robert J S Thomas; Rodney J Hicks
Journal:  Eur J Nucl Med Mol Imaging       Date:  2006-02-10       Impact factor: 9.236

6.  Whole-body FDG PET/CT is more accurate than conventional imaging for staging primary breast cancer patients.

Authors:  C Riegger; J Herrmann; J Nagarajah; J Hecktor; S Kuemmel; F Otterbach; S Hahn; A Bockisch; T Lauenstein; G Antoch; T A Heusner
Journal:  Eur J Nucl Med Mol Imaging       Date:  2012-03-06       Impact factor: 9.236

Review 7.  The role of positron emission tomographic imaging in breast cancer.

Authors:  Michelle D McDonough; Elizabeth R DePeri; Betty A Mincey
Journal:  Curr Oncol Rep       Date:  2004-01       Impact factor: 5.075

8.  Ovarian mass mimicking malignancy: a case report.

Authors:  Yong-Il Kim; Seok-Ki Kim; Jeong-Won Lee; Sang Mi Lee; Tae-Sung Kim
Journal:  Nucl Med Mol Imaging       Date:  2010-08-27

9.  Normal Physiologic and Benign Foci with F-18 FDG Avidity on PET/CT in Patients with Breast Cancer.

Authors:  Soon-Ah Park; Kwang-Man Lee; UnJong Choi; Hun Soo Kim; Hye-Won Kim; Jeong Hoon Song
Journal:  Nucl Med Mol Imaging       Date:  2010-10-16

10.  [18F]FDG in recurrent breast cancer: diagnostic performances, clinical impact and relevance of induced changes in management.

Authors:  Dany Grahek; Françoise Montravers; Khaldoun Kerrou; Nicolas Aide; Jean-Pierre Lotz; Jean-Noël Talbot
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-02       Impact factor: 9.236

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