An approach to estimating bone and joint loads and muscle strength in living subjects and skeletal remains.

Skeletal physiology that clarified after 1990 shows that bone modeling normally makes a bone strong enough to keep its loads from causing strains above a "modeling threshold". That arrangement adapts bone strength to the largest loads on a bone, which are usually brief and infrequent. Accordingly, in bone adapted chiefly to uniaxial compression loads, the modeling threshold's value and the cross-sectional amount of that bone could suggest the size of those loads. Bone loaded in that way does support the articular surfaces of synovial joints as their "supporting bone", so its amount could suggest the size of the loads it had adapted to, and therefore the loads on the joint that it supports. During growth a joint's size is proportional, directly but not linearly, to the size of its total loads, so that its size at skeletal maturity could be an index of those loads at that time. Joints cannot decrease in size. Yet throughout life their supporting bone can decrease or increase in strength and "mass" to adapt to changes in a joint's loads. Thus, an adult joint's size could suggest the size of the loads it adapted to by skeletal maturity, while the cross-sectional amount of its supporting bone at any later age could reveal the size of those loads at that later age, and thus suggest any change in those loads that might have occurred after skeletal maturity. Since the bone modeling threshold, and the relationships between bone strain, stress, and unit loads are now known, it is possible with this procedure to estimate the total loads on joints, and how body weight and muscle strength contribute to those loads in both living subjects and skeletal remains. To make a reliable technology of the idea involves some problems which this paper identifies and suggests how to resolve. Am. J. Hum. Biol. 11:437-455, 1999. Copyright 1999 Wiley-Liss, Inc.