Literature DB >> 11523946

Spinal chloroma presenting with triplegia in an aleukaemic patient.

M E Buckland1, R A Scolyer, M B Donellan, S Brew, M McGee-Collett, C G Harper.   

Abstract

Malignant myeloid blast cells may occasionally form a solid mass in tissues outside the haemopoietic system. These tumours are known as chloromas or granulocytic sarcomas. Chloromas occur most commonly in the context of acute myelogenous leukaemia but, rarely, they occur in the absence of other haematological disease, and may be misdiagnosed as lymphoma. A case of a previously well 35-year-old woman presenting with rapidly progressive triplegia caused by a paraspinal and extradural cervical chloroma with no evidence of bone marrow or other haematological involvement is described. Few cases of spinal cord compression caused by chloroma in otherwise healthy patients have been reported. Morphological features of myeloid differentiation, histochemistry and immunohistochemistry, may all aid in rapid diagnosis and allow early and appropriate therapy.

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Year:  2001        PMID: 11523946

Source DB:  PubMed          Journal:  Pathology        ISSN: 0031-3025            Impact factor:   5.306


  6 in total

Review 1.  Granulocytic sarcoma of the spine in a child without bone marrow involvement: a case report and literature review.

Authors:  Yusuke Shiozawa; Nobutaka Kiyokawa; Masahiro Saito; Junichiro Fujimoto; Jun-Ichi Hata; Yuichiro Yamashiro
Journal:  Eur J Pediatr       Date:  2005-07-13       Impact factor: 3.183

2.  Unusual case of paraplegia.

Authors:  Prem Amalraj; S Syamlal
Journal:  Ann Indian Acad Neurol       Date:  2009-07       Impact factor: 1.383

3.  Pathological dislocation of the dorsal spine following granulocytic sarcoma in a non-leukaemic patient.

Authors:  Rohit Amritanand; K Venkatesh; Anne J Premkumar; Gabriel D Sundararaj
Journal:  Eur Spine J       Date:  2009-08-18       Impact factor: 3.134

4.  Granulocytic sarcoma presenting as presenting as monoparesis: A rare case report.

Authors:  Ashok Gupta; Amit Chanduka; I Vijay Sundar; Jitender Verma; Sanjeev Chopra
Journal:  Asian J Neurosurg       Date:  2014 Oct-Dec

Review 5.  Diagnosis and surgical treatment of primary isolated aggressive lumbar myeloid sarcoma: a rare case report and review of the literatures.

Authors:  Cheng-Rui Bai; Xiang Li; Jing-Shi Wang; Jin-Jun Li; Ning Liu; Qi Fei; Dong Li; Yong Yang
Journal:  BMC Musculoskelet Disord       Date:  2021-02-24       Impact factor: 2.362

6.  Clinicopathologic features and responses to radiotherapy of myeloid sarcoma.

Authors:  Wan-Yu Chen; Chun-Wei Wang; Chin-Hao Chang; Heng-Hsiu Liu; Keng-Hsueh Lan; Jih-Luh Tang; Hwei-Fang Tien; Sung-Hsin Kuo; Ann-Lii Cheng
Journal:  Radiat Oncol       Date:  2013-10-22       Impact factor: 3.481

  6 in total

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