UNLABELLED: We report a 2-year-old Japanese boy without bone marrow involvement who developed a primary granulocytic sarcoma in his spinal canal. Tumour cells were positive for myeloperoxidase, MIC2, CD56 and, CD68 on formalin-fixed, paraffin-embedded tissue sections and CD13, CD33, CD45, and CD64 on acetone-fixed fresh frozen sections. Nine months after the initiation of treatment, the tumour had significantly regressed and the patient was able to walk with help. CONCLUSION: Our patient is the youngest case of granulocytic sarcoma of the spine without bone marrow involvement. Immunohistochemical methods are very helpful in establishing a diagnosis of granulocytic sarcoma.
UNLABELLED: We report a 2-year-old Japanese boy without bone marrow involvement who developed a primary granulocytic sarcoma in his spinal canal. Tumour cells were positive for myeloperoxidase, MIC2, CD56 and, CD68 on formalin-fixed, paraffin-embedded tissue sections and CD13, CD33, CD45, and CD64 on acetone-fixed fresh frozen sections. Nine months after the initiation of treatment, the tumour had significantly regressed and the patient was able to walk with help. CONCLUSION: Our patient is the youngest case of granulocytic sarcoma of the spine without bone marrow involvement. Immunohistochemical methods are very helpful in establishing a diagnosis of granulocytic sarcoma.
Authors: A-M Tsimberidou; H M Kantarjian; E Estey; J E Cortes; S Verstovsek; S Faderl; D A Thomas; G Garcia-Manero; A Ferrajoli; J T Manning; M J Keating; M Albitar; S O'Brien; F J Giles Journal: Leukemia Date: 2003-06 Impact factor: 11.528
Authors: Janpreet S Bhandohal; Leila Moosavi; Igor Garcia-Pacheco; Gian Yakoub; Rahul D Polineni; Everardo Cobos Journal: AME Case Rep Date: 2021-07-25