Literature DB >> 19688354

Pathological dislocation of the dorsal spine following granulocytic sarcoma in a non-leukaemic patient.

Rohit Amritanand1, K Venkatesh, Anne J Premkumar, Gabriel D Sundararaj.   

Abstract

We describe a previously healthy, non-leukaemic young male presenting with neurological deficit and a pathological dislocation of D8 over D9 vertebra. The magnetic resonance imaging showed an enhancing soft tissue tumour. His basic laboratory workup as well as a bone marrow biopsy was normal. Through a single midline posterior approach, he underwent a decompressive laminectomy of D8 and D9 vertebra, anterior column reconstruction with a meshed titanium cage and posterior pedicle screw instrumentation. The histological diagnosis of granulocytic sarcoma was confirmed by appropriate immuno-histochemical studies. He received postoperative radiotherapy following which his wound dehiscesed and the tumour fungated and spread to his left thigh. He declined chemotherapy and unfortunately expired 9 months later. This case is presented to draw attention to the unusual presentation and to stress that granulocytic sarcoma should be kept in mind when making the differential diagnosis in patients with signs of spinal cord compression even in non-leukaemic individuals.

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Mesh:

Year:  2009        PMID: 19688354      PMCID: PMC2899635          DOI: 10.1007/s00586-009-1132-4

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  13 in total

1.  Spontaneous dislocation of a vertebra in a patient who had neurofibromatosis. Report of a case with dural ectasia.

Authors:  R B Winter
Journal:  J Bone Joint Surg Am       Date:  1991-10       Impact factor: 5.284

Review 2.  Granulocytic sarcoma of the spine.

Authors:  H Mostafavi; P J Lennarson; V C Traynelis
Journal:  Neurosurgery       Date:  2000-01       Impact factor: 4.654

3.  Granulocytic sarcoma of the spine in nonleukemic patients: report of three cases.

Authors:  S Deme; S S Deodhare; W S Tucker; J M Bilbao
Journal:  Neurosurgery       Date:  1997-06       Impact factor: 4.654

4.  Spinal granulocytic sarcoma (chloroma) presenting as acute cord compression in a nonleukemic patient.

Authors:  Murat Kalayci; Murat Sümer; Sibel Yenidünya; Senay Ozdolap; Bektas Açikgöz
Journal:  Neurol India       Date:  2005-06       Impact factor: 2.117

5.  Charcot's disease of the spine: diagnosis and treatment.

Authors:  Raphaël Vialle; Pierre Mary; Jean-Louis Tassin; Fabrice Parker; Michel Guillaumat
Journal:  Spine (Phila Pa 1976)       Date:  2005-06-01       Impact factor: 3.468

6.  L5 sciatica as first symptom of a granulocytic sarcoma.

Authors:  D Roig-Vilaseca; B Yoldi; I Trias; A Pedro; R Garriga; A Renau
Journal:  Acta Oncol       Date:  1994       Impact factor: 4.089

7.  Spinal granulocytic sarcoma manifesting as radiculopathy in a nonleukemic patient.

Authors:  Tomoo Inoue; Toshiyuki Takahashi; Hiroaki Shimizu; Masayuki Kanamori; Toshihiro Kumabe; Mika Watanabe; Teiji Tominaga
Journal:  Neurol Med Chir (Tokyo)       Date:  2008-03       Impact factor: 1.742

8.  Granulocytic sarcoma preceding acute leukemia: a report of six cases.

Authors:  J R Krause
Journal:  Cancer       Date:  1979-09       Impact factor: 6.860

9.  Granulocytic sarcoma in nonleukemic patients.

Authors:  J M Meis; J J Butler; B M Osborne; J T Manning
Journal:  Cancer       Date:  1986-12-15       Impact factor: 6.860

10.  Simultaneous anterior decompression and posterior instrumentation of the tuberculous spine using an anterolateral extrapleural approach.

Authors:  A K Jain; I K Dhammi; B Prashad; S Sinha; P Mishra
Journal:  J Bone Joint Surg Br       Date:  2008-11
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  1 in total

Review 1.  Diagnosis and surgical treatment of primary isolated aggressive lumbar myeloid sarcoma: a rare case report and review of the literatures.

Authors:  Cheng-Rui Bai; Xiang Li; Jing-Shi Wang; Jin-Jun Li; Ning Liu; Qi Fei; Dong Li; Yong Yang
Journal:  BMC Musculoskelet Disord       Date:  2021-02-24       Impact factor: 2.362

  1 in total

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