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Literature DB >> 17851388

Syntheses and biological activities of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines.

Jian-yu Jin¹, Li-xue Zhang, Xian-xing Chen, An-jiang Zhang, Hai-le Zhang.

Abstract

A series of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]-thiadiazines were synthesized by the reaction of 4-amino-3-(3-hydroxypropyl)-5-mercapto-1,2,4-triazole (1) with substituted omega-haloacetophenones. Their structures were confirmed by elemental analysis, IR, 1H-NMR, and 13C-NMR. Tests of plant growth regulating effects showed that the title compounds display remarkable inhibitory activities on the growth of radish and wheat.

Entities: Chemical Species

Mesh：

Substances：

Year: 2007 PMID： 17851388 PMCID： PMC6149417 DOI： 10.3390/12030297

Source DB: PubMed Journal: Molecules ISSN： 1420-3049 Impact factor: 4.411

3 in total

1. Studies on nitrophenylfuran derivatives part Xii. synthesis, characterization, antibacterial and antiviral activities of some nitrophenylfurfurylidene-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.

Authors: B S Holla; P M Akberali; M K Shivananda
Journal: Farmaco Date: 2001-12

2. Synthesis and anthelmintic activity of 3,6-disubstituted-7H-s-triazolo(3,4-b)(1,3,4)thiadiazines.

Authors: B A Nadkarni; V R Kamat; B G Khadse
Journal: Arzneimittelforschung Date: 2001

3. Synthesis and studies on some new fluorine containing triazolothiadiazines as possible antibacterial, antifungal and anticancer agents.

Authors: B Shivarama Holla; B Sooryanarayana Rao; B K Sarojini; P M Akberali; N Suchetha Kumari
Journal: Eur J Med Chem Date: 2006-04-17 Impact factor: 6.514

3 in total

4 in total

1. Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole.

Authors: Jian-yu Jin; Li-xue Zhang; An-jiang Zhang; Xin-Xiang Lei; Jiang-Hai Zhu
Journal: Molecules Date: 2007-07-27 Impact factor: 4.411

Syntheses and biological activities of 6-aryl-3-(3-hydroxypropyl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines.

1. Studies on nitrophenylfuran derivatives part Xii. synthesis, characterization, antibacterial and antiviral activities of some nitrophenylfurfurylidene-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.

2. Synthesis and anthelmintic activity of 3,6-disubstituted-7H-s-triazolo(3,4-b)(1,3,4)thiadiazines.

3. Synthesis and studies on some new fluorine containing triazolothiadiazines as possible antibacterial, antifungal and anticancer agents.

1. Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole.

2. Antimicrobial studies of unsymmetrical bis-1,2,3-triazoles.

Review 3. Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold.

Review 4. Two decades of the synthesis of mono- and bis-aminomercapto[1,2,4]triazoles.