Literature DB >> 11504627

The glucose-regulated proteins: stress induction and clinical applications.

A S Lee1.   

Abstract

A protective mechanism used by cells to adapt to stress of the endoplasmic reticulum (ER) is the induction of members of the glucose-regulated protein (Grp) family. The induction of mammalian Grp proteins in response to ER stress involves a complex network of regulators and novel mechanisms. The elucidation of Grp function and regulation opens up new therapeutic approaches to diseases associated with ER stress and cancer.

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Year:  2001        PMID: 11504627     DOI: 10.1016/s0968-0004(01)01908-9

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  344 in total

1.  SHEPHERD is the Arabidopsis GRP94 responsible for the formation of functional CLAVATA proteins.

Authors:  Sumie Ishiguro; Yuhko Watanabe; Natsuko Ito; Hideko Nonaka; Norimasa Takeda; Tomoko Sakai; Hiroshi Kanaya; Kiyotaka Okada
Journal:  EMBO J       Date:  2002-03-01       Impact factor: 11.598

2.  Tissue-specific regulation of BiP genes: a cis-acting regulatory domain is required for BiP promoter activity in plant meristems.

Authors:  Reginaldo A A Buzeli; Júlio C M Cascardo; Leonardo A Z Rodrigues; Maxuel O Andrade; Raul S Almeida; Marcelo E Loureiro; Wagner C Otoni; Elizabeth P B Fontes
Journal:  Plant Mol Biol       Date:  2002-11       Impact factor: 4.076

Review 3.  The mammalian endoplasmic reticulum as a sensor for cellular stress.

Authors:  Yanjun Ma; Linda M Hendershot
Journal:  Cell Stress Chaperones       Date:  2002-04       Impact factor: 3.667

Review 4.  Orchestrating the unfolded protein response in health and disease.

Authors:  Randal J Kaufman
Journal:  J Clin Invest       Date:  2002-11       Impact factor: 14.808

5.  Ameliorative effects of selenium on the excess apoptosis of the jejunum caused by AFB1 through death receptor and endoplasmic reticulum pathways.

Authors:  Jing Fang; Zhixiang Zheng; Zhuangzhi Yang; Xi Peng; Zhicai Zuo; Hengmin Cui; Ping Ouyang; Gang Shu; Zhengli Chen; Chao Huang
Journal:  Toxicol Res (Camb)       Date:  2018-07-04       Impact factor: 3.524

6.  The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.

Authors:  Yue Wei; Tapan Kadia; Weigang Tong; Ming Zhang; Yu Jia; Hui Yang; Yumin Hu; Francesco Paolo Tambaro; Jean Viallet; Susan O'Brien; Guillermo Garcia-Manero
Journal:  Clin Cancer Res       Date:  2010-06-10       Impact factor: 12.531

Review 7.  GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum.

Authors:  Michal Marzec; Davide Eletto; Yair Argon
Journal:  Biochim Biophys Acta       Date:  2011-11-03

Review 8.  Molecular targeting of proteins by L-homocysteine: mechanistic implications for vascular disease.

Authors:  Alla V Glushchenko; Donald W Jacobsen
Journal:  Antioxid Redox Signal       Date:  2007-11       Impact factor: 8.401

9.  Correlation between clinicopathology and expression of heat shock protein 70 and glucose-regulated protein 94 in human colonic adenocarcinoma.

Authors:  Xiao-Ping Wang; Fan-Rong Qiu; Guo-Zhen Liu; Rui-Fen Chen
Journal:  World J Gastroenterol       Date:  2005-02-21       Impact factor: 5.742

10.  GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.

Authors:  Gidi Shani; Wolfgang H Fischer; Nicholas J Justice; Jonathan A Kelber; Wylie Vale; Peter C Gray
Journal:  Mol Cell Biol       Date:  2007-11-08       Impact factor: 4.272

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