| Literature DB >> 12380691 |
Yanjun Ma1, Linda M Hendershot.
Abstract
The recent elucidation of the mammalian unfolded protein response pathway has revealed a unique and transcriptionally complex signal transduction pathway that protects cells from a variety of physical and biochemical stresses that can occur during normal development and in disease states. Although the stress conditions are monitored in the endoplasmic reticulum, the beneficial effects of this pathway are extended to other cellular organelles and to the organism itself.Entities:
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Year: 2002 PMID: 12380691 PMCID: PMC514821 DOI: 10.1379/1466-1268(2002)007<0222:tmeraa>2.0.co;2
Source DB: PubMed Journal: Cell Stress Chaperones ISSN: 1355-8145 Impact factor: 3.667