Literature DB >> 1149016

Effects of high-molecular levan on the growth and spread of lymphoma in AKR mice.

J Leibovici, Y Sinai, M Wolman, G Davidai.   

Abstract

Levan was shown to inhibit lymphoma development in AKR mice. Growth of tumor was inhibited at the site of injection and in metastases. Levan caused a decrease in the incidence of tumors, and it reduced pleomorphism, mitoses, and invasiveness of tumors in comparison to nonlevanized mice. Evidence of tumor cell destruction was observed in levanized mice. The effect of levan on tumor development was dose dependent.

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Year:  1975        PMID： 1149016

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  9 in total

1.  Modification of the tuberculin reaction by levan.

Authors:  E Shezen; J Leibovici; M Wolman
Journal:  Br J Exp Pathol       Date:  1978-10

2.  Suppression of humoral immune response in mice by administration of high molecular levan.

Authors:  S Hoenig; I Katzap; J Leibovici
Journal:  Experientia       Date:  1978-10-15

3.  Different biological behavior of AKR lymphoma cells from primary and metastatic tumors.

Authors:  J Leibovici; Y Stark; S Kopel
Journal:  Experientia       Date:  1985-03-15

4.  Spontaneous AKR lymphomas differ in their degree of malignancy and sensitivity to the polysaccharide levan.

Authors:  J Leibovici
Journal:  Experientia       Date:  1983-03-15

5.  Combined effect of levan and cytotoxic agents on the growth of experimental tumours in mice.

Authors:  J Leibovici; Y Stark; M Wolman
Journal:  Br J Exp Pathol       Date:  1983-06

6.  Different effects of the polysaccharide levan on the oncogenicity of cells of two variants of Lewis lung carcinoma.

Authors:  Y Stark; J Leibovici
Journal:  Br J Exp Pathol       Date:  1986-02

7.  Histological changes in spleen and lymph nodes of mice administered cyclophosphamide and levan.

Authors:  A Siegal; S Kopel; J Leibovici
Journal:  Cell Tissue Res       Date:  1986       Impact factor: 5.249

8.  Mechanism of the anti-tumour effect of glucans and fructosans: a comparison with C. parvum.

Authors:  R Bomford; C Moreno
Journal:  Br J Cancer       Date:  1977-07       Impact factor: 7.640

9.  The role of macrophages and polymorphs in the levan-induced inhibition of Lewis lung carcinoma in C57BL mice.

Authors:  J Leibovici; A Borit; U Sandbank; M Wolman
Journal:  Br J Cancer       Date:  1979-10       Impact factor: 7.640
  9 in total

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