Literature DB >> 3947532

Different effects of the polysaccharide levan on the oncogenicity of cells of two variants of Lewis lung carcinoma.

Y Stark, J Leibovici.   

Abstract

A marked difference in sensitivity to the direct effect of the polysaccharide levan on tumour cells was observed between two variants of malignancy of Lewis lung carcinoma: cells of the more malignant variant (3LL-M) were much more sensitive to the drug than those of the less malignant tumour (3LL). A gradual decrease in tumorigenicity following preincubation with increasing levan concentrations was observed with both variants, but statistically significant inhibition was observed at lower levan concentrations with 3LL-M than with 3LL.

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Year:  1986        PMID: 3947532      PMCID: PMC2013074     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  19 in total

1.  Effects of route and schedule of administration of high-molecular levan on the growth of AKR lymphoma.

Authors:  Y Sinai; J Leibovici; M Wolman
Journal:  Cancer Res       Date:  1976-05       Impact factor: 12.701

2.  Effects of high-molecular levan on the growth and spread of lymphoma in AKR mice.

Authors:  J Leibovici; Y Sinai; M Wolman; G Davidai
Journal:  Cancer Res       Date:  1975-08       Impact factor: 12.701

Review 3.  Surface glycoproteins of malignant human leukocytes.

Authors:  C G Gahmberg; L C Andersson
Journal:  Biochim Biophys Acta       Date:  1982-04-29

4.  Adriamycin effect on the Lewis lung carcinoma. Comparison between the original line and its derivative subline.

Authors:  C Greco; F Calbresi; M Caputo; A Corsi; A Sacchi; G Zupi
Journal:  Eur J Cancer       Date:  1980-09       Impact factor: 9.162

5.  Characterization of a deficiency in fucose metabolism in lectin-resistant variants of a murine tumor showing altered tumorigenic and metastatic capacities in vivo.

Authors:  J W Dennis; R S Kerbel
Journal:  Cancer Res       Date:  1981-01       Impact factor: 12.701

Review 6.  Animal models for tumor progression (short review).

Authors:  J Leibovici; M Wolman
Journal:  Anticancer Res       Date:  1984 May-Jun       Impact factor: 2.480

7.  Increased synthesis of hyaluronic acid by mouse mammary carcinoma cell variants with high metastatic potential.

Authors:  K Kimata; Y Honma; M Okayama; K Oguri; M Hozumi; S Suzuki
Journal:  Cancer Res       Date:  1983-03       Impact factor: 12.701

8.  Establishment and immunologic characterization of 3-methylcholanthrene-induced sarcoma cell lines metastasizing widely in mice and exhibiting distinct and selective propensities for the mode of metastasis.

Authors:  Y Kodama; T Seyama; K Kamiya; K Yokoro
Journal:  J Natl Cancer Inst       Date:  1982-09       Impact factor: 13.506

9.  Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms.

Authors:  M A Cifone; I J Fidler
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

10.  Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples.

Authors:  R Peto; M C Pike; P Armitage; N E Breslow; D R Cox; S V Howard; N Mantel; K McPherson; J Peto; P G Smith
Journal:  Br J Cancer       Date:  1977-01       Impact factor: 7.640

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