HYPOTHESIS: Immediate enteral feeding following major abdominal surgery reduces postoperative complications and mortality when compared with parenteral nutrition. DESIGN: A prospective multicenter randomized trial. SETTING:A university hospital department of digestive surgery. PATIENTS AND INTERVENTIONS:Two hundred forty-one malnourished patients undergoing major elective abdominal surgery were randomly assigned to receive, after surgery, either enteral (enteral nutritiongroup: 119 patients) orparenteral nutrition (total parenteral nutritiongroup: 122 patients). The patients were monitored for postoperative complications and mortality. RESULTS: The rate of major postoperative complications was similar in the enteral and parenteral groups (enteral nutrition group: 37.8%; total parenteral nutrition group: 39.3%; P was not significant), as were the overall postoperative mortality rates (5.9% and 2.5%, respectively; P was not significant). CONCLUSION: The present study failed to demonstrate that enteral feeding following major abdominal surgery reduces postoperative complications and mortality when compared with parenteral nutrition.
RCT Entities:
HYPOTHESIS: Immediate enteral feeding following major abdominal surgery reduces postoperative complications and mortality when compared with parenteral nutrition. DESIGN: A prospective multicenter randomized trial. SETTING: A university hospital department of digestive surgery. PATIENTS AND INTERVENTIONS: Two hundred forty-one malnourished patients undergoing major elective abdominal surgery were randomly assigned to receive, after surgery, either enteral (enteral nutrition group: 119 patients) or parenteral nutrition (total parenteral nutrition group: 122 patients). The patients were monitored for postoperative complications and mortality. RESULTS: The rate of major postoperative complications was similar in the enteral and parenteral groups (enteral nutrition group: 37.8%; total parenteral nutrition group: 39.3%; P was not significant), as were the overall postoperative mortality rates (5.9% and 2.5%, respectively; P was not significant). CONCLUSION: The present study failed to demonstrate that enteral feeding following major abdominal surgery reduces postoperative complications and mortality when compared with parenteral nutrition.
Authors: Ronald Chow; Eduardo Bruera; Jann Arends; Declan Walsh; Florian Strasser; Elisabeth Isenring; Egidio G Del Fabbro; Alex Molassiotis; Monica Krishnan; Leonard Chiu; Nicholas Chiu; Stephanie Chan; Tian Yi Tang; Henry Lam; Michael Lock; Carlo DeAngelis Journal: Support Care Cancer Date: 2019-12-07 Impact factor: 3.603
Authors: A Weimann; Ch Ebener; S Holland-Cunz; K W Jauch; L Hausser; M Kemen; L Kraehenbuehl; E R Kuse; F Laengle Journal: Ger Med Sci Date: 2009-11-18
Authors: Marianne J Chapman; Robert J L Fraser; Geoffrey Matthews; Antonietta Russo; Max Bellon; Laura K Besanko; Karen L Jones; Ross Butler; Barry Chatterton; Michael Horowitz Journal: Crit Care Date: 2009-08-27 Impact factor: 9.097
Authors: Ali Ghafouri; Omran Abbas Salehi; Seyed Ali Keshavarz; Saeed Hosseini; Abolfazl Shojaifard; Zhamak Khorgami Journal: Med J Islam Repub Iran Date: 2012-02