Literature DB >> 11483227

Second-generation Hybrid capture test and Amplicor monitor test generate highly correlated hepatitis B virus DNA levels.

M Poljak1, I J Marin, K Seme, V Brinovec, M Maticic, J Meglic-Volkar, G Lesnicar, A Vince.   

Abstract

The performance of the Digene Hybrid Capture II HBV DNA Test HC II and the Roche Cobas Amplicor Monitor Test (Cobas-HBV) was evaluated on 252 serum samples. One hundred and seventy-three samples were HBV DNA positive and 75 HBV DNA negative by both assays. Four samples were HBV DNA positive by Cobas-HBV only. Linear regression analysis showed that the HBV DNA concentrations obtained from both assays were significantly related (n=173, r=0.976, P<0.0001). The results of the study show that Hybrid capture II and Cobas-HBV could be used equally in the management for patients with chronic HBV infection.

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Year:  2001        PMID: 11483227     DOI: 10.1016/s0166-0934(01)00359-7

Source DB:  PubMed          Journal:  J Virol Methods        ISSN: 0166-0934            Impact factor:   2.014


  3 in total

1.  Evaluation of the COBAS amplicor HBV monitor assay and comparison with the ultrasensitive HBV hybrid capture 2 assay for quantification of hepatitis B virus DNA.

Authors:  Eric Q Konnick; Maria Erali; Edward R Ashwood; David R Hillyard
Journal:  J Clin Microbiol       Date:  2005-02       Impact factor: 5.948

2.  Inhibitory effect of oxymatrine on serum hepatitis B virus DNA in HBV transgenic mice.

Authors:  Lun-Gen Lu; Min-De Zeng; Yi-Min Mao; Jing-Yuan Fang; Yu-Lin Song; Zhao-Hui Shen; Ai-Ping Cao
Journal:  World J Gastroenterol       Date:  2004-04-15       Impact factor: 5.742

3.  Clinical evaluation of the digene hybrid capture II test and the COBAS AMPLICOR monitor test for determination of hepatitis B virus DNA levels.

Authors:  He-Jun Yuan; Man-Fung Yuen; Danny Ka-Ho Wong; Simon Siu-Man Sum; Ching-Lung Lai
Journal:  J Clin Microbiol       Date:  2004-08       Impact factor: 5.948

  3 in total

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