O Zmora1, P Gervaz, S D Wexner. 1. Department of Colorectal Surgery, Cleveland Clinic Florida, 3000 West Cypress Creek Road, Fort Lauderdale, FL 33309, USA.
Abstract
BACKGROUND: Laparoscopic colorectal surgery has been associated with less postoperative pain, an early return of bowel function, a shorter period of hospitalization and disability, and better cosmetic results. However, the application of laparoscopic techniques to the curative resection of colorectal cancer is still controversial, owing to reports of cancer recurrence at the port site wounds. The accumulation of numerous such reports in a relatively short period raised concern that there might be an extraordinary high rate of port site metastases after laparoscopic colorectal surgery. This concern has led to intense clinical and basic research aimed at determining the incidence and causes of wound recurrence and developing preventative measures to address this problem. Despite these efforts, it is still not clear whether port site metastasis is really an inherent drawback to laparoscopic cancer surgery. METHODS: In this review of the literature on port site metastasis, we gathered data from clinical series of laparoscopic surgery for colorectal cancer. We eliminated series of <50 patients, since they may be flawed by the learning curve required for this technically demanding procedure. RESULTS: The rate of port site recurrences in the 1737 patients who participated in these series was 1%. Although the methods and criteria for patient selection in these studies varied, this figure appears to be comparable to the incidence reported for other malignancies and for laparotomies performed to treat colorectal cancer. CONCLUSION: This review suggests that wound recurrence may actually be the result of an unfortunate learning curve, rather than an inherent concern. However, we must await the final results of large randomized studies before drawing any definitive conclusions.
BACKGROUND: Laparoscopic colorectal surgery has been associated with less postoperative pain, an early return of bowel function, a shorter period of hospitalization and disability, and better cosmetic results. However, the application of laparoscopic techniques to the curative resection of colorectal cancer is still controversial, owing to reports of cancer recurrence at the port site wounds. The accumulation of numerous such reports in a relatively short period raised concern that there might be an extraordinary high rate of port site metastases after laparoscopic colorectal surgery. This concern has led to intense clinical and basic research aimed at determining the incidence and causes of wound recurrence and developing preventative measures to address this problem. Despite these efforts, it is still not clear whether port site metastasis is really an inherent drawback to laparoscopic cancer surgery. METHODS: In this review of the literature on port site metastasis, we gathered data from clinical series of laparoscopic surgery for colorectal cancer. We eliminated series of <50 patients, since they may be flawed by the learning curve required for this technically demanding procedure. RESULTS: The rate of port site recurrences in the 1737 patients who participated in these series was 1%. Although the methods and criteria for patient selection in these studies varied, this figure appears to be comparable to the incidence reported for other malignancies and for laparotomies performed to treat colorectal cancer. CONCLUSION: This review suggests that wound recurrence may actually be the result of an unfortunate learning curve, rather than an inherent concern. However, we must await the final results of large randomized studies before drawing any definitive conclusions.
Authors: J W Fleshman; H Nelson; W R Peters; H C Kim; S Larach; R R Boorse; W Ambroze; P Leggett; R Bleday; S Stryker; B Christenson; S Wexner; A Senagore; D Rattner; J Sutton; A P Fine Journal: Dis Colon Rectum Date: 1996-10 Impact factor: 4.585
Authors: P Vukasin; A E Ortega; F L Greene; G D Steele; A J Simons; G J Anthone; L A Weston; R W Beart Journal: Dis Colon Rectum Date: 1996-10 Impact factor: 4.585
Authors: D B Jones; L W Guo; M K Reinhard; N J Soper; G W Philpott; J Connett; J W Fleshman Journal: Dis Colon Rectum Date: 1995-11 Impact factor: 4.585
Authors: Sebastian Senger; Jens Sperling; Barbara Oberkircher; Martin K Schilling; Otto Kollmar; Michael D Menger; Christian Ziemann Journal: Clin Exp Metastasis Date: 2017-06-19 Impact factor: 5.150