Literature DB >> 11439080

Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product.

H E Pelish, N J Westwood, Y Feng, T Kirchhausen, M D Shair.   

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Year:  2001        PMID： 11439080     DOI： 10.1021/ja016093h

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  31 in total

1.  Trifunctional norrisolide probes for the study of Golgi vesiculation.

Authors:  Gianni Guizzunti; Thomas P Brady; Vivek Malhotra; Emmanuel A Theodorakis
Journal:  Bioorg Med Chem Lett       Date:  2006-11-06       Impact factor: 2.823

2.  Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors.

Authors:  Brian C Goess; Rami N Hannoush; Lawrence K Chan; Tomas Kirchhausen; Matthew D Shair
Journal:  J Am Chem Soc       Date:  2006-04-26       Impact factor: 15.419

Review 3.  Natural products as sources of new drugs over the 30 years from 1981 to 2010.

Authors:  David J Newman; Gordon M Cragg
Journal:  J Nat Prod       Date:  2012-02-08       Impact factor: 4.050

4.  A road less traveled by: exploring a decade of Ellman chemistry.

Authors:  Anang A Shelat; R Kiplin Guy
Journal:  Bioorg Med Chem       Date:  2008-03-04       Impact factor: 3.641

5.  Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis.

Authors:  Tom Kirchhausen; Eric Macia; Henry E Pelish
Journal:  Methods Enzymol       Date:  2008       Impact factor: 1.600

6.  Synthesis of a novel suppressor of beta-cell apoptosis via diversity-oriented synthesis.

Authors:  Danny Hung-Chieh Chou; Jeremy R Duvall; Baudouin Gerard; Haibo Liu; Bhaumik A Pandya; Byung-Chul Suh; Erin M Forbeck; Patrick Faloon; Bridget K Wagner; Lisa A Marcaurelle
Journal:  ACS Med Chem Lett       Date:  2011-09-08       Impact factor: 4.345

7.  Chemical biology studies on norrisolide.

Authors:  Gianni Guizzunti; Thomas P Brady; Derek Fischer; Vivek Malhotra; Emmanuel A Theodorakis
Journal:  Bioorg Med Chem       Date:  2010-02-10       Impact factor: 3.641

8.  Golgi-modifying properties of macfarlandin E and the synthesis and evaluation of its 2,7-dioxabicyclo[3.2.1]octan-3-one core.

Authors:  Martin J Schnermann; Christopher M Beaudry; Anastasia V Egorova; Roman S Polishchuk; Christine Sütterlin; Larry E Overman
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-23       Impact factor: 11.205

9.  Combinatorial catalysis employing a visible enzymatic beacon in real time: synthetically versatile (pseudo)halometalation/carbocyclizations.

Authors:  Jacob A Friest; Sylvain Broussy; Woo Jin Chung; David B Berkowitz
Journal:  Angew Chem Int Ed Engl       Date:  2011-08-16       Impact factor: 15.336

10.  A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products.

Authors:  Robert W Huigens; Karen C Morrison; Robert W Hicklin; Timothy A Flood; Michelle F Richter; Paul J Hergenrother
Journal:  Nat Chem       Date:  2013-01-20       Impact factor: 24.427
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