Literature DB >> 11435167

Role of short RNAs in gene silencing.

P M Waterhouse1, M B Wang, E J Finnegan.   

Abstract

Recent research has revealed the existence of an elegant defence mechanism in plants and lower eukaryotes. The mechanism, known in plants as post-transcriptional gene silencing, works through sequence-specific degradation of RNA. It appears to be directed by double-stranded RNA, associated with the production of short 21-25 nt RNAs, and spread through the plant by a diffusible signal. The short RNAs are implicated as the guides for both a nuclease complex that degrades the mRNA and a methyltransferase complex that methylates the DNA of silenced genes. It has also been suggested that these short RNAs might be the mobile silencing signal, a suggestion that has been challenged recently.

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Year:  2001        PMID： 11435167     DOI： 10.1016/s1360-1385(01)01989-6

Source DB:  PubMed          Journal:  Trends Plant Sci        ISSN： 1360-1385            Impact factor:   18.313


  18 in total

1.  Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting post-transcriptional gene silencing.

Authors:  Alexandra Boutla; Kriton Kalantidis; Nektarios Tavernarakis; Mina Tsagris; Martin Tabler
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

2.  Suppression of sucrose synthase gene expression represses cotton fiber cell initiation, elongation, and seed development.

Authors:  Yong-Ling Ruan; Danny J Llewellyn; Robert T Furbank
Journal:  Plant Cell       Date:  2003-04       Impact factor: 11.277

Review 3.  RNA interference: biology, mechanism, and applications.

Authors:  Neema Agrawal; P V N Dasaradhi; Asif Mohmmed; Pawan Malhotra; Raj K Bhatnagar; Sunil K Mukherjee
Journal:  Microbiol Mol Biol Rev       Date:  2003-12       Impact factor: 11.056

4.  A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs.

Authors:  Dániel Silhavy; Attila Molnár; Alessandra Lucioli; György Szittya; Csaba Hornyik; Mario Tavazza; József Burgyán
Journal:  EMBO J       Date:  2002-06-17       Impact factor: 11.598

5.  High molecular weight RNAs and small interfering RNAs induce systemic posttranscriptional gene silencing in plants.

Authors:  Ulrich Klahre; Patrice Crété; Sabrina A Leuenberger; Victor A Iglesias; Frederick Meins
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-14       Impact factor: 11.205

Review 6.  Gene silencing-based disease resistance.

Authors:  Michael Wassenegger
Journal:  Transgenic Res       Date:  2002-12       Impact factor: 2.788

7.  Low temperature inhibits RNA silencing-mediated defence by the control of siRNA generation.

Authors:  György Szittya; Dániel Silhavy; Attila Molnár; Zoltán Havelda; Agnes Lovas; Lóránt Lakatos; Zsófia Bánfalvi; József Burgyán
Journal:  EMBO J       Date:  2003-02-03       Impact factor: 11.598

8.  Deletion derivatives of the MuDR regulatory transposon of maize encode antisense transcripts but are not dominant-negative regulators of mutator activities.

Authors:  Soo-Hwan Kim; Virginia Walbot
Journal:  Plant Cell       Date:  2003-09-24       Impact factor: 11.277

9.  Arabidopsis variegation mutants.

Authors:  Steven Rodermel
Journal:  Arabidopsis Book       Date:  2002-03-27

10.  RNA interference-mediated gene silencing of vascular endothelial growth factor in colon cancer cells.

Authors:  Tie-Jun Li; Jian-Ning Song; Kai Kang; Shu-Sheng Tong; Zan-Lan Hu; Tong-Chuan He; Bing-Qiang Zhang; Cai-Quan Zhang
Journal:  World J Gastroenterol       Date:  2007-10-28       Impact factor: 5.742
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