| Literature DB >> 11432595 |
M Es-Souni1, M Es-Souni1, H F Brandies.
Abstract
The transformation behaviour, mechanical properties and cytotoxicity of a binary NiTi42 and a ternary NiTi42Cu7 alloy have been investigated. The transformation temperatures were determined via differential scanning calorimetry, the mechanical properties have been investigated in 3-point bending tests in the temperature range between 6 and 60 degrees C. The cytotoxicity tests were performed on both alloys in cultured epithelial cells from human gingiva. The cytotoxicity investigations included both MTT tests and morphological observations. It is shown that although the ternary alloy is characterised by a narrower hysteresis and superior mechanical properties, including fatigue resistance, its cytotoxicity is higher than that of the binary alloy. This is thought to arise from the release of copper ions in the medium, which upon atomic absorption spectroscopy measurements amount to approximately 2.8 microg cm(-2) for an incubation period of 7 days.Entities:
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Year: 2001 PMID: 11432595 DOI: 10.1016/s0142-9612(00)00406-3
Source DB: PubMed Journal: Biomaterials ISSN: 0142-9612 Impact factor: 12.479