| Literature DB >> 11374955 |
T J Hsieh1, F R Chang, Y C Chia, C Y Chen, H F Chiu, Y C Wu.
Abstract
A new guaipyridine sesquiterpene alkaloid, cananodine (1), and two new eudesmane sesquiterpenes, cryptomeridiol 11-alpha-L-rhamnoside (2) and gamma-eudesmol 11-alpha-L-rhamnoside (3), along with gamma-eudesmol (4), were isolated from the fruits of Cananga odorata. The structures of compounds 1-3 were established on the basis of NMR and MS methods. In addition, compounds 1-4 and four previously reported alkaloids, cleistopholine (5), N-trans-feruloyltyramine (6), (+)-ushinsunine-beta-N-oxide (7), and lyscamine (8), were evaluated for cytotoxicity against two human hepatocarcinoma cell lines.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11374955 DOI: 10.1021/np0005208
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050