Literature DB >> 11359931

Dribble, the Drosophila KRR1p homologue, is involved in rRNA processing.

H Y Chan1, S Brogna, C J O'Kane.   

Abstract

The Drosophila dribble (dbe) gene encodes a KH domain protein, homologous to yeast KRR1p. Expression of dbe transcripts is ubiquitous during embryogenesis. Overexpressed Dribble protein is localized in the nucleus and in some cell types in a subregion of the nucleolus. Homozygous dbe mutants die at first instar larval stage. Clonal analyses suggest that dbe(+) is required for survival of dividing cells. In dbe mutants, a novel rRNA-processing defect is found and accumulation of an abnormal rRNA precursor is detected.

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Year:  2001        PMID： 11359931      PMCID： PMC34593          DOI： 10.1091/mbc.12.5.1409

Source DB:  PubMed          Journal:  Mol Biol Cell        ISSN： 1059-1524            Impact factor:   4.138


  49 in total

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Review 2.  The HIV-1 Rev protein.

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3.  The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster.

Authors:  T B Chou; N Perrimon
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4.  Specificity of PS integrin function during embryogenesis resides in the alpha subunit extracellular domain.

Authors:  M D Martin-Bermudo; O M Dunin-Borkowski; N H Brown
Journal:  EMBO J       Date:  1997-07-16       Impact factor: 11.598

5.  Subnucleolar location of fibrillarin and variation in its levels during the cell cycle and during differentiation of plant cells.

Authors:  A Cerdido; F J Medina
Journal:  Chromosoma       Date:  1995-05       Impact factor: 4.316

6.  A novel cross-phylum family of proteins comprises a KRR1 (YCL059c) gene which is essential for viability of Saccharomyces cerevisiae cells.

Authors:  R Gromadka; A Kaniak; P P Slonimski; J Rytka
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Review 7.  Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels.

Authors:  B Miroux; J E Walker
Journal:  J Mol Biol       Date:  1996-07-19       Impact factor: 5.469

Review 8.  The nucleolus: an old factory with unexpected capabilities.

Authors:  M O Olson; M Dundr; A Szebeni
Journal:  Trends Cell Biol       Date:  2000-05       Impact factor: 20.808

9.  The pre-mRNA binding K protein contains a novel evolutionarily conserved motif.

Authors:  H Siomi; M J Matunis; W M Michael; G Dreyfuss
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10.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

Authors:  A H Brand; N Perrimon
Journal:  Development       Date:  1993-06       Impact factor: 6.868
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  15 in total

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2.  Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana.

Authors:  Zdravko J Lorković; Andrea Barta
Journal:  Nucleic Acids Res       Date:  2002-02-01       Impact factor: 16.971

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4.  Interaction between ribosome assembly factors Krr1 and Faf1 is essential for formation of small ribosomal subunit in yeast.

Authors:  Sanduo Zheng; Pengfei Lan; Ximing Liu; Keqiong Ye
Journal:  J Biol Chem       Date:  2014-07-02       Impact factor: 5.157

5.  Crystallization and preliminary crystallographic analysis of the central domain of Drosophila Dribble, a protein that is essential for ribosome biogenesis.

Authors:  Tat Cheung Cheng; Yu Wai Chen; Kam Bo Wong; Sai-Ming Ngai; H Y Edwin Chan
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-04-29

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7.  Poly(A) signals located near the 5' end of genes are silenced by a general mechanism that prevents premature 3'-end processing.

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8.  Gene drive that results in addiction to a temperature-sensitive version of an essential gene triggers population collapse in Drosophila.

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9.  RNAi knockdown of Nopp140 induces Minute-like phenotypes in Drosophila.

Authors:  Zhengfang Cui; Patrick J DiMario
Journal:  Mol Biol Cell       Date:  2007-03-28       Impact factor: 4.138

10.  Genetic screening for modifiers of the DREF pathway in Drosophila melanogaster: identification and characterization of HP6 as a novel target of DREF.

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Journal:  Nucleic Acids Res       Date:  2009-01-09       Impact factor: 16.971
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