Literature DB >> 11358542

Effects of the oral spirochete Treponema denticola on interleukin-8 expression from epithelial cells.

Q D Deng1, Y Han, X Xia, H K Kuramitsu.   

Abstract

This communication demonstrates that the interaction of the oral spirochete Treponema denticola 35405 with KB epithelial cells does not lead to the induction of interleukin-8 production as occurs with a variety of other bacteria. Utilizing the dentilisin protease mutant K1 of T. denticola, this property was demonstrated to be primarily a function of the expression of the protease by strain 35405.

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Year:  2001        PMID: 11358542     DOI: 10.1034/j.1399-302x.2001.016003185.x

Source DB:  PubMed          Journal:  Oral Microbiol Immunol        ISSN: 0902-0055


  13 in total

Review 1.  Flagellar motility of the pathogenic spirochetes.

Authors:  Charles W Wolgemuth
Journal:  Semin Cell Dev Biol       Date:  2015-10-17       Impact factor: 7.727

2.  Treponema denticola PrcB is required for expression and activity of the PrcA-PrtP (dentilisin) complex.

Authors:  Valentina Godovikova; Hong-Tao Wang; M Paula Goetting-Minesky; Yu Ning; Ricardo F Capone; Claudia K Slater; J Christopher Fenno
Journal:  J Bacteriol       Date:  2010-04-30       Impact factor: 3.490

3.  Mutagenesis of a novel gene in the prcA-prtP protease locus affects expression of Treponema denticola membrane complexes.

Authors:  Xue-Lin Bian; Hong-Tao Wang; Yu Ning; Si Young Lee; J Christopher Fenno
Journal:  Infect Immun       Date:  2005-02       Impact factor: 3.441

4.  Mechanisms of decreased susceptibility to beta-defensins by Treponema denticola.

Authors:  Catherine A Brissette; Sheila A Lukehart
Journal:  Infect Immun       Date:  2007-02-26       Impact factor: 3.441

5.  Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells.

Authors:  C A Brissette; T-T T Pham; S R Coats; R P Darveau; S A Lukehart
Journal:  Oral Microbiol Immunol       Date:  2008-12

6.  Role for recombinant gamma-glutamyltransferase from Treponema denticola in glutathione metabolism.

Authors:  Lianrui Chu; Xiaoping Xu; Zheng Dong; David Cappelli; Jefferey L Ebersole
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

7.  Oral treponemes and their outer membrane extracts activate human gingival epithelial cells through toll-like receptor 2.

Authors:  Yasuyuki Asai; Takayoshi Jinno; Tomohiko Ogawa
Journal:  Infect Immun       Date:  2003-02       Impact factor: 3.441

8.  The Treponema denticola surface protease dentilisin degrades interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alpha.

Authors:  Meguru Miyamoto; Kazuyuki Ishihara; Katsuji Okuda
Journal:  Infect Immun       Date:  2006-04       Impact factor: 3.441

9.  Treponema denticola is resistant to human beta-defensins.

Authors:  Catherine A Brissette; Sheila A Lukehart
Journal:  Infect Immun       Date:  2002-07       Impact factor: 3.441

10.  Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens.

Authors:  Suk Ji; Youngnim Choi
Journal:  J Periodontal Implant Sci       Date:  2013-02-28       Impact factor: 2.614

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