Literature DB >> 16552080

The Treponema denticola surface protease dentilisin degrades interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alpha.

Meguru Miyamoto1, Kazuyuki Ishihara, Katsuji Okuda.   

Abstract

Dentilisin is a major surface protease and virulence factor of the bacterium Treponema denticola. In this study, we found that T. denticola reduced inflammatory cytokines, including interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor alpha, in peripheral blood mononuclear cells through degradation by dentilisin.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16552080      PMCID： PMC1418930          DOI： 10.1128/IAI.74.4.2462-2467.2006

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  39 in total

1.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

Authors:  K J Livak; T D Schmittgen
Journal:  Methods       Date:  2001-12       Impact factor: 3.608

2.  Relative distribution of bacteria at clinically healthy and periodontally diseased sites in humans.

Authors:  M A Listgarten; L Helldén
Journal:  J Clin Periodontol       Date:  1978-05       Impact factor: 8.728

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

4.  The opdB locus encodes the trypsin-like peptidase activity of Treponema denticola.

Authors:  J C Fenno; S Y Lee; C H Bayer; Y Ning
Journal:  Infect Immun       Date:  2001-10       Impact factor: 3.441

5.  Characterization of the immunocompetent cells in human advanced periodontitis.

Authors:  H Okada; T Kida; H Yamagami
Journal:  J Periodontal Res       Date:  1982-09       Impact factor: 4.419

6.  Immunoglobulin bearing lymphocytes and plasma cells in human periodontal disease.

Authors:  B F Mackler; K B Frostad; P B Robertson; B M Levy
Journal:  J Periodontal Res       Date:  1977-01       Impact factor: 4.419

7.  Relationship between the percentage of subgingival spirochetes and the severity of periodontal disease.

Authors:  G C Armitage; W R Dickinson; R S Jenderseck; S M Levine; D W Chambers
Journal:  J Periodontol       Date:  1982-09       Impact factor: 6.993

8.  Bacteriology of moderate (chronic) periodontitis in mature adult humans.

Authors:  W E Moore; L V Holdeman; E P Cato; R M Smibert; J A Burmeister; R R Ranney
Journal:  Infect Immun       Date:  1983-11       Impact factor: 3.441

9.  Mixed infections with Porphyromonas gingivalis and Treponema denticola cause excessive inflammatory responses in a mouse pneumonia model compared with monoinfections.

Authors:  Ryuta Kimizuka; Tetsuo Kato; Kazuyuki Ishihara; Katsuji Okuda
Journal:  Microbes Infect       Date:  2003-12       Impact factor: 2.700

10.  Host response in experimental periodontal disease.

Authors:  M A Taubman; H Yoshie; J L Ebersole; D J Smith; C L Olson
Journal:  J Dent Res       Date:  1984-03       Impact factor: 6.116
View more
  24 in total

Review 1.  Virulence factors of the oral spirochete Treponema denticola.

Authors:  S G Dashper; C A Seers; K H Tan; E C Reynolds
Journal:  J Dent Res       Date:  2010-10-12       Impact factor: 6.116

2.  Treponema denticola chymotrypsin-like proteinase (CTLP) integrates spirochaetes within oral microbial communities.

Authors:  Valentina Cogoni; Alex Morgan-Smith; J Christopher Fenno; Howard F Jenkinson; David Dymock
Journal:  Microbiology       Date:  2012-02-07       Impact factor: 2.777

3.  Comparative genomic analyses of attenuated strains of Mycoplasma gallisepticum.

Authors:  S M Szczepanek; E R Tulman; T S Gorton; X Liao; Z Lu; J Zinski; F Aziz; S Frasca; G F Kutish; S J Geary
Journal:  Infect Immun       Date:  2010-02-01       Impact factor: 3.441

4.  Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles.

Authors:  V Bakthavatchalu; A Meka; S Sathishkumar; M C Lopez; R K Verma; S M Wallet; I Bhattacharyya; B F Boyce; J J Mans; R J Lamont; H V Baker; J L Ebersole; L Kesavalu
Journal:  Mol Oral Microbiol       Date:  2010-08       Impact factor: 3.563

5.  Identification of the primary mechanism of complement evasion by the periodontal pathogen, Treponema denticola.

Authors:  J V McDowell; J Frederick; D P Miller; M P Goetting-Minesky; H Goodman; J C Fenno; R T Marconi
Journal:  Mol Oral Microbiol       Date:  2010-12-03       Impact factor: 3.563

6.  Analysis of the complement sensitivity of oral treponemes and the potential influence of FH binding, FH cleavage and dentilisin activity on the pathogenesis of periodontal disease.

Authors:  D P Miller; J V McDowell; J K Bell; M P Goetting-Minesky; J C Fenno; R T Marconi
Journal:  Mol Oral Microbiol       Date:  2014-06-03       Impact factor: 3.563

7.  Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells.

Authors:  C A Brissette; T-T T Pham; S R Coats; R P Darveau; S A Lukehart
Journal:  Oral Microbiol Immunol       Date:  2008-12

8.  Transcriptional profiles of Treponema denticola in response to environmental conditions.

Authors:  Ian McHardy; Caroline Keegan; Jee-Hyun Sim; Wenyuan Shi; Renate Lux
Journal:  PLoS One       Date:  2010-10-27       Impact factor: 3.240

9.  A pathogenic trace of Tannerella forsythia - shedding of soluble fully active tumor necrosis factor α from the macrophage surface by karilysin.

Authors:  D Bryzek; M Ksiazek; E Bielecka; A Y Karim; B Potempa; D Staniec; J Koziel; J Potempa
Journal:  Mol Oral Microbiol       Date:  2014-10-03       Impact factor: 3.563

10.  Treponema denticola alters cell vitality and induces HO-1 and Hsp70 expression in porcine aortic endothelial cells.

Authors:  Chiara Bernardini; Paolo Gaibani; Augusta Zannoni; Caterina Vocale; Maria Laura Bacci; Gabriela Piana; Monica Forni; Vittorio Sambri
Journal:  Cell Stress Chaperones       Date:  2009-12-20       Impact factor: 3.667
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.