Literature DB >> 11292782

Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils.

R Cockeran1, H C Steel, T J Mitchell, C Feldman, R Anderson.   

Abstract

Exposure to pneumolysin (8.37 and 41.75 ng/ml) caused a calcium-dependent increase in the generation of prostaglandin E(2) and leukotriene B(4) by both resting and chemoattractant-activated human neutrophils in vitro. These interactions of pneumolysin with neutrophils may result in dysregulation of inflammatory responses during pneumococcal infection.

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Year:  2001        PMID： 11292782      PMCID： PMC98318          DOI： 10.1128/IAI.69.5.3494-3496.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  10 in total

1.  Host cellular immune response to pneumococcal lung infection in mice.

Authors:  A Kadioglu; N A Gingles; K Grattan; A Kerr; T J Mitchell; P W Andrew
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

2.  Autooxidation as a basis for altered function by polymorphonuclear leukocytes.

Authors:  R L Baehner; L A Boxer; J M Allen; J Davis
Journal:  Blood       Date:  1977-08       Impact factor: 22.113

3.  Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity.

Authors:  F K Saunders; T J Mitchell; J A Walker; P W Andrew; G J Boulnois
Journal:  Infect Immun       Date:  1989-08       Impact factor: 3.441

Review 4.  Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs.

Authors:  H E Claesson; S E Dahlén
Journal:  J Intern Med       Date:  1999-03       Impact factor: 8.989

5.  Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide: differential susceptibility of human lymphocyte functions.

Authors:  A el-Hag; P E Lipsky; M Bennett; R A Clark
Journal:  J Immunol       Date:  1986-05-01       Impact factor: 5.422

6.  Pneumolysin, a protein toxin of Streptococcus pneumoniae, induces nitric oxide production from macrophages.

Authors:  J S Braun; R Novak; G Gao; P J Murray; J L Shenep
Journal:  Infect Immun       Date:  1999-08       Impact factor: 3.441

7.  Proinflammatory interactions of pneumolysin with human neutrophils.

Authors:  R Cockeran; A J Theron; H C Steel; N M Matlola; T J Mitchell; C Feldman; R Anderson
Journal:  J Infect Dis       Date:  2001-01-17       Impact factor: 5.226

8.  Agents that elevate cAMP inhibit human neutrophil apoptosis.

Authors:  A G Rossi; J M Cousin; I Dransfield; M F Lawson; E R Chilvers; C Haslett
Journal:  Biochem Biophys Res Commun       Date:  1995-12-26       Impact factor: 3.575

9.  Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1 beta by human mononuclear phagocytes.

Authors:  S Houldsworth; P W Andrew; T J Mitchell
Journal:  Infect Immun       Date:  1994-04       Impact factor: 3.441

10.  Pneumolysin activates phospholipase A in pulmonary artery endothelial cells.

Authors:  J B Rubins; T J Mitchell; P W Andrew; D E Niewoehner
Journal:  Infect Immun       Date:  1994-09       Impact factor: 3.441
  10 in total
  26 in total

1.  Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity.

Authors:  Hisashi Baba; Ikuo Kawamura; Chikara Kohda; Takamasa Nomura; Yutaka Ito; Terumi Kimoto; Isao Watanabe; Satoshi Ichiyama; Masao Mitsuyama
Journal:  Infect Immun       Date:  2002-01       Impact factor: 3.441

Review 2.  Bacteraemic pneumococcal pneumonia: current therapeutic options.

Authors:  Charles Feldman; Ronald Anderson
Journal:  Drugs       Date:  2011-01-22       Impact factor: 9.546

3.  Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone.

Authors:  Annette Spreer; Holger Kerstan; Tobias Böttcher; Joachim Gerber; Alexander Siemer; Gregor Zysk; Timothy J Mitchell; Helmut Eiffert; Roland Nau
Journal:  Antimicrob Agents Chemother       Date:  2003-08       Impact factor: 5.191

Review 4.  Membrane assembly of the cholesterol-dependent cytolysin pore complex.

Authors:  Eileen M Hotze; Rodney K Tweten
Journal:  Biochim Biophys Acta       Date:  2011-07-31

5.  Epithelial cells are sensitive detectors of bacterial pore-forming toxins.

Authors:  Adam J Ratner; Karen R Hippe; Jorge L Aguilar; Matthew H Bender; Aaron L Nelson; Jeffrey N Weiser
Journal:  J Biol Chem       Date:  2006-03-06       Impact factor: 5.157

Review 6.  Prostaglandin E2 as a Regulator of Immunity to Pathogens.

Authors:  Giovanny J Martínez-Colón; Bethany B Moore
Journal:  Pharmacol Ther       Date:  2017-12-22       Impact factor: 12.310

7.  THP-1 monocytes up-regulate intercellular adhesion molecule 1 in response to pneumolysin from Streptococcus pneumoniae.

Authors:  Justin Thornton; Larry S McDaniel
Journal:  Infect Immun       Date:  2005-10       Impact factor: 3.441

8.  The pore-forming toxin listeriolysin O is degraded by neutrophil metalloproteinase-8 and fails to mediate Listeria monocytogenes intracellular survival in neutrophils.

Authors:  Eusondia Arnett; Stephen Vadia; Colleen C Nackerman; Steve Oghumu; Abhay R Satoskar; Kenneth R McLeish; Silvia M Uriarte; Stephanie Seveau
Journal:  J Immunol       Date:  2013-12-06       Impact factor: 5.422

9.  Pneumolysin activates neutrophil extracellular trap formation.

Authors:  J G Nel; A J Theron; C Durandt; G R Tintinger; R Pool; T J Mitchell; C Feldman; R Anderson
Journal:  Clin Exp Immunol       Date:  2016-03-02       Impact factor: 4.330

10.  The Multifaceted Roles Neutrophils Play in the Tumor Microenvironment.

Authors:  Ronit Vogt Sionov; Zvi G Fridlender; Zvi Granot
Journal:  Cancer Microenviron       Date:  2014-06-04
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