Literature DB >> 11292764

Passive immunization with melanin-binding monoclonal antibodies prolongs survival of mice with lethal Cryptococcus neoformans infection.

A L Rosas1, J D Nosanchuk, A Casadevall.   

Abstract

Passive immunization with monoclonal antibodies (MAbs) to melanin prolonged the survival of and reduced the fungal burden in Cryptococcus neoformans-infected mice in comparison to controls. MAbs to melanin reduced the growth rate of in vitro-melanized C. neoformans cells, suggesting a new mechanism of antibody-mediated protection.

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Year:  2001        PMID: 11292764      PMCID: PMC98300          DOI: 10.1128/IAI.69.5.3410-3412.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  9 in total

1.  Extracellular proteinase activity of Cryptococcus neoformans.

Authors:  L C Chen; E S Blank; A Casadevall
Journal:  Clin Diagn Lab Immunol       Date:  1996-09

2.  Monoclonal antibodies to surface antigens of Mycobacterium tuberculosis and their use in a modified enzyme-linked immunosorbent spot assay for detection of mycobacteria.

Authors:  A Glatman-Freedman; J M Martin; P F Riska; B R Bloom; A Casadevall
Journal:  J Clin Microbiol       Date:  1996-11       Impact factor: 5.948

Review 3.  Virulence factors of Cryptococcus neoformans.

Authors:  T R Kozel
Journal:  Trends Microbiol       Date:  1995-08       Impact factor: 17.079

Review 4.  Melanin and virulence in Cryptococcus neoformans.

Authors:  A Casadevall; A L Rosas; J D Nosanchuk
Journal:  Curr Opin Microbiol       Date:  2000-08       Impact factor: 7.934

5.  Melanisation of Cryptococcus neoformans in human brain tissue.

Authors:  J D Nosanchuk; A L Rosas; S C Lee; A Casadevall
Journal:  Lancet       Date:  2000-06-10       Impact factor: 79.321

6.  Human antibodies against a purified glucosylceramide from Cryptococcus neoformans inhibit cell budding and fungal growth.

Authors:  M L Rodrigues; L R Travassos; K R Miranda; A J Franzen; S Rozental; W de Souza; C S Alviano; E Barreto-Bergter
Journal:  Infect Immun       Date:  2000-12       Impact factor: 3.441

Review 7.  Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans.

Authors:  T G Mitchell; J R Perfect
Journal:  Clin Microbiol Rev       Date:  1995-10       Impact factor: 26.132

8.  Synthesis of polymerized melanin by Cryptococcus neoformans in infected rodents.

Authors:  A L Rosas; J D Nosanchuk; M Feldmesser; G M Cox; H C McDade; A Casadevall
Journal:  Infect Immun       Date:  2000-05       Impact factor: 3.441

9.  Melanization of Cryptococcus neoformans in murine infection.

Authors:  J D Nosanchuk; P Valadon; M Feldmesser; A Casadevall
Journal:  Mol Cell Biol       Date:  1999-01       Impact factor: 4.272

  9 in total
  42 in total

Review 1.  An insight into the antifungal pipeline: selected new molecules and beyond.

Authors:  Luis Ostrosky-Zeichner; Arturo Casadevall; John N Galgiani; Frank C Odds; John H Rex
Journal:  Nat Rev Drug Discov       Date:  2010-08-20       Impact factor: 84.694

2.  Pathogen-specific antibodies: codependent no longer.

Authors:  Edward N Janoff; Daniel N Frank
Journal:  J Clin Invest       Date:  2010-03-24       Impact factor: 14.808

3.  Treatment of early and established Cryptococcus neoformans infection with radiolabeled antibodies in immunocompetent mice.

Authors:  Zewei Jiang; Ruth A Bryan; Alfred Morgenstern; Frank Bruchertseifer; Arturo Casadevall; Ekaterina Dadachova
Journal:  Antimicrob Agents Chemother       Date:  2011-10-17       Impact factor: 5.191

4.  Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism.

Authors:  Erin E McClelland; André M Nicola; Rafael Prados-Rosales; Arturo Casadevall
Journal:  J Clin Invest       Date:  2010-03-24       Impact factor: 14.808

Review 5.  New concepts in antibody-mediated immunity.

Authors:  Arturo Casadevall; Liise-anne Pirofski
Journal:  Infect Immun       Date:  2004-11       Impact factor: 3.441

Review 6.  Impact of melanin on microbial virulence and clinical resistance to antimicrobial compounds.

Authors:  Joshua D Nosanchuk; Arturo Casadevall
Journal:  Antimicrob Agents Chemother       Date:  2006-11       Impact factor: 5.191

Review 7.  Antibody-mediated protection through cross-reactivity introduces a fungal heresy into immunological dogma.

Authors:  Arturo Casadevall; Liise-anne Pirofski
Journal:  Infect Immun       Date:  2007-08-20       Impact factor: 3.441

8.  Monoclonal antibody to fungal glucosylceramide protects mice against lethal Cryptococcus neoformans infection.

Authors:  Marcio L Rodrigues; Li Shi; Eliana Barreto-Bergter; Leonardo Nimrichter; Sandra E Farias; Elaine G Rodrigues; Luiz R Travassos; Joshua D Nosanchuk
Journal:  Clin Vaccine Immunol       Date:  2007-08-22

9.  Melanin from Fonsecaea pedrosoi induces production of human antifungal antibodies and enhances the antimicrobial efficacy of phagocytes.

Authors:  Daniela S Alviano; Anderson J Franzen; Luiz R Travassos; Carla Holandino; Sonia Rozental; Regina Ejzemberg; Celuta S Alviano; Marcio L Rodrigues
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

10.  Vesicular transport across the fungal cell wall.

Authors:  Arturo Casadevall; Joshua D Nosanchuk; Peter Williamson; Marcio L Rodrigues
Journal:  Trends Microbiol       Date:  2009-03-18       Impact factor: 17.079

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