Literature DB >> 8528612

Virulence factors of Cryptococcus neoformans.

T R Kozel1.   

Abstract

Cryptococcosis is a serious fungal disease in patients with AIDS or other defects in T-cell-mediated host defenses. Cryptococcus neoformans produces several virulence factors, most notably the polysaccharide capsule and phenol oxidase. Molecular studies of cryptococcal virulence factors have contributed to our understanding of the pathobiology of this yeast, and will enable the identification of new targets for antifungal therapy.

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Year:  1995        PMID: 8528612     DOI: 10.1016/s0966-842x(00)88957-x

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  29 in total

1.  Pleiotropic function of intersectin homologue Cin1 in Cryptococcus neoformans.

Authors:  Gui Shen; Amy Whittington; Kejing Song; Ping Wang
Journal:  Mol Microbiol       Date:  2010-03-16       Impact factor: 3.501

2.  Vesicular polysaccharide export in Cryptococcus neoformans is a eukaryotic solution to the problem of fungal trans-cell wall transport.

Authors:  Marcio L Rodrigues; Leonardo Nimrichter; Débora L Oliveira; Susana Frases; Kildare Miranda; Oscar Zaragoza; Mauricio Alvarez; Antonio Nakouzi; Marta Feldmesser; Arturo Casadevall
Journal:  Eukaryot Cell       Date:  2006-11-17

3.  A collagenous protective coat enables Metarhizium anisopliae to evade insect immune responses.

Authors:  Chengshu Wang; Raymond J St Leger
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-13       Impact factor: 11.205

4.  The Mouse Inhalation Model of Cryptococcus neoformans Infection Recapitulates Strain Virulence in Humans and Shows that Closely Related Strains Can Possess Differential Virulence.

Authors:  Liliane Mukaremera; Tami R McDonald; Judith N Nielsen; Christopher J Molenaar; Andrew Akampurira; Charlotte Schutz; Kabanda Taseera; Conrad Muzoora; Graeme Meintjes; David B Meya; David R Boulware; Kirsten Nielsen
Journal:  Infect Immun       Date:  2019-04-23       Impact factor: 3.441

Review 5.  Virulence mechanisms and Cryptococcus neoformans pathogenesis.

Authors:  J Andrew Alspaugh
Journal:  Fungal Genet Biol       Date:  2014-09-23       Impact factor: 3.495

6.  Role of mannoprotein in induction and regulation of immunity to Cryptococcus neoformans.

Authors:  D Pietrella; R Cherniak; C Strappini; S Perito; P Mosci; F Bistoni; A Vecchiarelli
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

7.  Passive immunization with melanin-binding monoclonal antibodies prolongs survival of mice with lethal Cryptococcus neoformans infection.

Authors:  A L Rosas; J D Nosanchuk; A Casadevall
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

8.  Self-aggregation of Cryptococcus neoformans capsular glucuronoxylomannan is dependent on divalent cations.

Authors:  Leonardo Nimrichter; Susana Frases; Leonardo P Cinelli; Nathan B Viana; Antonio Nakouzi; Luiz R Travassos; Arturo Casadevall; Marcio L Rodrigues
Journal:  Eukaryot Cell       Date:  2007-06-15

9.  Aggregation of Cryptococcus neoformans by surfactant protein D is inhibited by its capsular component glucuronoxylomannan.

Authors:  J K van de Wetering; F E J Coenjaerts; A B Vaandrager; L M G van Golde; J J Batenburg
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

10.  A Ric8/synembryn homolog promotes Gpa1 and Gpa2 activation to respectively regulate cyclic AMP and pheromone signaling in Cryptococcus neoformans.

Authors:  Jinjun Gong; Jacob D Grodsky; Zhengguang Zhang; Ping Wang
Journal:  Eukaryot Cell       Date:  2014-08-01
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