| Literature DB >> 8528612 |
Abstract
Cryptococcosis is a serious fungal disease in patients with AIDS or other defects in T-cell-mediated host defenses. Cryptococcus neoformans produces several virulence factors, most notably the polysaccharide capsule and phenol oxidase. Molecular studies of cryptococcal virulence factors have contributed to our understanding of the pathobiology of this yeast, and will enable the identification of new targets for antifungal therapy.Entities:
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Year: 1995 PMID: 8528612 DOI: 10.1016/s0966-842x(00)88957-x
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079