Literature DB >> 17715331

Monoclonal antibody to fungal glucosylceramide protects mice against lethal Cryptococcus neoformans infection.

Marcio L Rodrigues1, Li Shi, Eliana Barreto-Bergter, Leonardo Nimrichter, Sandra E Farias, Elaine G Rodrigues, Luiz R Travassos, Joshua D Nosanchuk.   

Abstract

Glucosylceramides (GlcCer) are involved in the regulation of Cryptococcus neoformans virulence. In the present study, we demonstrate that passive immunization with a monoclonal antibody to GlcCer significantly reduces host inflammation and prolongs the survival of mice lethally infected with C. neoformans, revealing a potential therapeutic strategy to control cryptococcosis.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17715331      PMCID： PMC2168121          DOI： 10.1128/CVI.00202-07

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  40 in total

1.  Cytokine and chemokine expression in the central nervous system associated with protective cell-mediated immunity against Cryptococcus neoformans.

Authors:  William C Uicker; Hester A Doyle; James P McCracken; Mary Langlois; Kent L Buchanan
Journal:  Med Mycol       Date:  2005-02       Impact factor: 4.076

Review 2.  Cross-protection by anti-core glycolipid antibodies: evidence from animal experiments.

Authors:  W N Hustinx; K Kraaijeveld; A I Hoepelman; J Verhoef
Journal:  J Antimicrob Chemother       Date:  1997-10       Impact factor: 5.790

3.  Effect of antibody to capsular polysaccharide on eosinophilic pneumonia in murine infection with Cryptococcus neoformans.

Authors:  M Feldmesser; Y Kress; A Casadevall
Journal:  J Infect Dis       Date:  1998-06       Impact factor: 5.226

4.  IL-12 protects mice against pulmonary and disseminated infection caused by Cryptococcus neoformans.

Authors:  K Kawakami; M Tohyama; Q Xie; A Saito
Journal:  Clin Exp Immunol       Date:  1996-05       Impact factor: 4.330

5.  Antibody-mediated protection against Cryptococcus neoformans pulmonary infection is dependent on B cells.

Authors:  Johanna Rivera; Oscar Zaragoza; Arturo Casadevall
Journal:  Infect Immun       Date:  2005-02       Impact factor: 3.441

6.  Role of IgG and complement component C5 in the initial course of experimental cryptococcosis.

Authors:  F Dromer; C Perronne; J Barge; J L Vilde; P Yeni
Journal:  Clin Exp Immunol       Date:  1989-12       Impact factor: 4.330

7.  Effect of serum IgG1 to Cryptococcus neoformans glucuronoxylomannan on murine pulmonary infection.

Authors:  M Feldmesser; A Casadevall
Journal:  J Immunol       Date:  1997-01-15       Impact factor: 5.422

8.  Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies.

Authors:  A Casadevall; W Cleare; M Feldmesser; A Glatman-Freedman; D L Goldman; T R Kozel; N Lendvai; J Mukherjee; L A Pirofski; J Rivera; A L Rosas; M D Scharff; P Valadon; K Westin; Z Zhong
Journal:  Antimicrob Agents Chemother       Date:  1998-06       Impact factor: 5.191

9.  Production, characterization, and antibody specificity of a mouse monoclonal antibody reactive with Cryptococcus neoformans capsular polysaccharide.

Authors:  F Dromer; J Salamero; A Contrepois; C Carbon; P Yeni
Journal:  Infect Immun       Date:  1987-03       Impact factor: 3.441

10.  Melanization of Cryptococcus neoformans in murine infection.

Authors:  J D Nosanchuk; P Valadon; M Feldmesser; A Casadevall
Journal:  Mol Cell Biol       Date:  1999-01       Impact factor: 4.272
View more
  38 in total

1.  Protective effect of fungal extracellular vesicles against murine candidiasis.

Authors:  Gabriele Vargas; Leandro Honorato; Allan Jefferson Guimarães; Marcio L Rodrigues; Flavia C G Reis; André M Vale; Anjana Ray; Joshua Daniel Nosanchuk; Leonardo Nimrichter
Journal:  Cell Microbiol       Date:  2020-07-22       Impact factor: 3.715

Review 2.  The protective role of immunoglobulins in fungal infections and inflammation.

Authors:  Sri Ramulu Elluru; Srini V Kaveri; Jagadeesh Bayry
Journal:  Semin Immunopathol       Date:  2014-11-18       Impact factor: 9.623

Review 3.  Drugs in Clinical Development for Fungal Infections.

Authors:  Maria F Gonzalez-Lara; Jose Sifuentes-Osornio; Luis Ostrosky-Zeichner
Journal:  Drugs       Date:  2017-09       Impact factor: 9.546

Review 4.  Vesicular transport systems in fungi.

Authors:  Marcio L Rodrigues; Joshua D Nosanchuk; Augusto Schrank; Marilene H Vainstein; Arturo Casadevall; Leonardo Nimrichter
Journal:  Future Microbiol       Date:  2011-11       Impact factor: 3.165

5.  Detection of antibody against fungal glucosylceramide in immunocompromised patients: a potential new diagnostic approach for cryptococcosis.

Authors:  Asfia Qureshi; Dannah Wray; Ryan Rhome; William Barry; Maurizio Del Poeta
Journal:  Mycopathologia       Date:  2011-10-05       Impact factor: 2.574

6.  In vitro activity of the antifungal plant defensin RsAFP2 against Candida isolates and its in vivo efficacy in prophylactic murine models of candidiasis.

Authors:  Patricia M Tavares; Karin Thevissen; Bruno P A Cammue; Isabelle E J A François; Eliana Barreto-Bergter; Carlos P Taborda; Alexandre F Marques; Marcio L Rodrigues; Leonardo Nimrichter
Journal:  Antimicrob Agents Chemother       Date:  2008-09-29       Impact factor: 5.191

7.  Binding of the wheat germ lectin to Cryptococcus neoformans chitooligomers affects multiple mechanisms required for fungal pathogenesis.

Authors:  Fernanda L Fonseca; Allan J Guimarães; Lívia Kmetzsch; Fabianno F Dutra; Fernanda D Silva; Carlos P Taborda; Glauber de S Araujo; Susana Frases; Charley C Staats; Marcelo T Bozza; Augusto Schrank; Marilene H Vainstein; Leonardo Nimrichter; Arturo Casadevall; Marcio L Rodrigues
Journal:  Fungal Genet Biol       Date:  2013-04-19       Impact factor: 3.495

Review 8.  Fungal sphingolipids: role in the regulation of virulence and potential as targets for future antifungal therapies.

Authors:  Caroline Mota Fernandes; Maurizio Del Poeta
Journal:  Expert Rev Anti Infect Ther       Date:  2020-07-16       Impact factor: 5.091

Review 9.  Plasma membrane lipids and their role in fungal virulence.

Authors:  Antonella Rella; Amir M Farnoud; Maurizio Del Poeta
Journal:  Prog Lipid Res       Date:  2015-12-15       Impact factor: 16.195

Review 10.  A Call to Arms: Quest for a Cryptococcal Vaccine.

Authors:  Marley C Caballero Van Dyke; Floyd L Wormley
Journal:  Trends Microbiol       Date:  2017-11-02       Impact factor: 17.079
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.