PURPOSE: To investigate the possible influence of different times of the day on multifocal ERG recordings in normals. METHODS: 10 healthy volunteers underwent multifocal ERG recordings (VERIS 3.1.1.) 3 times a day, at 10:30 am, 1:30 pm and 4:30 pm using a fast flicker stimulus of 103 hexagons. Additional night-time recordings were performed in 2 subjects. The first-order and dominant part of the second order response component were analyzed. RESULTS: Neither peak latencies nor peak-to-peak amplitudes showed significant changes during the day (p >0.05). Comparison between night and day time recordings did also not reveal an influence of a circadian rhythm on the MF-ERG. CONCLUSIONS: No significant influence of the time of the day suggestive of a circadian rhythm could be observed. Light adaptation due to preadaptation and the flicker sequence used could be a possible cause for these results.
PURPOSE: To investigate the possible influence of different times of the day on multifocal ERG recordings in normals. METHODS: 10 healthy volunteers underwent multifocal ERG recordings (VERIS 3.1.1.) 3 times a day, at 10:30 am, 1:30 pm and 4:30 pm using a fast flicker stimulus of 103 hexagons. Additional night-time recordings were performed in 2 subjects. The first-order and dominant part of the second order response component were analyzed. RESULTS: Neither peak latencies nor peak-to-peak amplitudes showed significant changes during the day (p >0.05). Comparison between night and day time recordings did also not reveal an influence of a circadian rhythm on the MF-ERG. CONCLUSIONS: No significant influence of the time of the day suggestive of a circadian rhythm could be observed. Light adaptation due to preadaptation and the flicker sequence used could be a possible cause for these results.
Authors: Pantea Moghimi; Nathalia Torres Jimenez; Linda K McLoon; Theoden I Netoff; Michael S Lee; Angus MacDonald; Robert F Miller Journal: Schizophr Res Date: 2019-10-12 Impact factor: 4.939