Literature DB >> 11284710

Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins.

D J Gillooly1, A Simonsen, H Stenmark.   

Abstract

PtdIns3P is a phosphoinositide 3-kinase product that has been strongly implicated in regulating membrane trafficking in both mammalian and yeast cells. PtdIns3P has been shown to be specifically located on membranes associated with the endocytic pathway. Proteins that contain FYVE zinc-finger domains are recruited to PtdIns3P-containing membranes. Structural information is now available concerning the interaction between FYVE domains and PtdIns3P. A number of proteins have been identified which contain a FYVE domain, and in this review we discuss the functions of PtdIns3P and its FYVE-domain-containing effector proteins in membrane trafficking, cytoskeletal regulation and receptor signalling.

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Year:  2001        PMID： 11284710      PMCID： PMC1221734          DOI： 10.1042/0264-6021:3550249

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  76 in total

1.  Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction.

Authors:  Y Mao; A Nickitenko; X Duan; T E Lloyd; M N Wu; H Bellen; F A Quiocho
Journal:  Cell       Date:  2000-02-18       Impact factor: 41.582

Review 2.  Regulation of signal transduction by endocytosis.

Authors:  B P Ceresa; S L Schmid
Journal:  Curr Opin Cell Biol       Date:  2000-04       Impact factor: 8.382

Review 3.  The role of phosphoinositide 3-kinase lipid products in cell function.

Authors:  L E Rameh; L C Cantley
Journal:  J Biol Chem       Date:  1999-03-26       Impact factor: 5.157

4.  The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization.

Authors:  D C Lawe; V Patki; R Heller-Harrison; D Lambright; S Corvera
Journal:  J Biol Chem       Date:  2000-02-04       Impact factor: 5.157

5.  The Rab5 effector EEA1 is a core component of endosome docking.

Authors:  S Christoforidis; H M McBride; R D Burgoyne; M Zerial
Journal:  Nature       Date:  1999-02-18       Impact factor: 49.962

Review 6.  Signalling through phosphoinositide 3-kinases: the lipids take centre stage.

Authors:  S J Leevers; B Vanhaesebroeck; M D Waterfield
Journal:  Curr Opin Cell Biol       Date:  1999-04       Impact factor: 8.382

7.  The role of the pleckstrin homology domain in membrane targeting and activation of phospholipase Cbeta(1).

Authors:  G Razzini; A Brancaccio; M A Lemmon; S Guarnieri; M Falasca
Journal:  J Biol Chem       Date:  2000-05-19       Impact factor: 5.157

8.  The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.

Authors:  J Callaghan; A Simonsen; J M Gaullier; B H Toh; H Stenmark
Journal:  Biochem J       Date:  1999-03-01       Impact factor: 3.857

9.  Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A.

Authors:  C Ostermeier; A T Brunger
Journal:  Cell       Date:  1999-02-05       Impact factor: 41.582

10.  Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

Authors:  A Bolino; M Muglia; F L Conforti; E LeGuern; M A Salih; D M Georgiou; K Christodoulou; I Hausmanowa-Petrusewicz; P Mandich; A Schenone; A Gambardella; F Bono; A Quattrone; M Devoto; A P Monaco
Journal:  Nat Genet       Date:  2000-05       Impact factor: 38.330
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  66 in total

1.  Hrs recruits clathrin to early endosomes.

Authors:  C Raiborg; K G Bache; A Mehlum; E Stang; H Stenmark
Journal:  EMBO J       Date:  2001-09-03       Impact factor: 11.598

Review 2.  Innovative techniques and applications in histochemistry and cell biology.

Authors:  Esther Asan
Journal:  Histochem Cell Biol       Date:  2003-11-28       Impact factor: 4.304

3.  Intrahippocampal wortmannin infusion enhances long-term spatial and contextual memories.

Authors:  Pramod K Dash; Sara A Mach; Sonja Blum; Anthony N Moore
Journal:  Learn Mem       Date:  2002 Jul-Aug       Impact factor: 2.460

Review 4.  Modulation and utilization of host cell phosphoinositides by Salmonella spp.

Authors:  Dan Drecktrah; Leigh A Knodler; Olivia Steele-Mortimer
Journal:  Infect Immun       Date:  2004-08       Impact factor: 3.441

5.  Xenopus laevis zygote arrest 2 (zar2) encodes a zinc finger RNA-binding protein that binds to the translational control sequence in the maternal Wee1 mRNA and regulates translation.

Authors:  Amanda Charlesworth; Tomomi M Yamamoto; Jonathan M Cook; Kevin D Silva; Cassandra V Kotter; Gwendolyn S Carter; Justin W Holt; Heather F Lavender; Angus M MacNicol; Yi Ying Wang; Anna Wilczynska
Journal:  Dev Biol       Date:  2012-06-23       Impact factor: 3.582

6.  ZF21 protein regulates cell adhesion and motility.

Authors:  Makoto Nagano; Daisuke Hoshino; Takeharu Sakamoto; Noritaka Kawasaki; Naohiko Koshikawa; Motoharu Seiki
Journal:  J Biol Chem       Date:  2010-05-03       Impact factor: 5.157

7.  Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis.

Authors:  Frédéric A Meunier; Shona L Osborne; Gerald R V Hammond; Frank T Cooke; Peter J Parker; Jan Domin; Giampietro Schiavo
Journal:  Mol Biol Cell       Date:  2005-07-29       Impact factor: 4.138

8.  Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes.

Authors:  Seyed Ali Mousavi; Andreas Brech; Trond Berg; Rune Kjeken
Journal:  Biochem J       Date:  2003-06-15       Impact factor: 3.857

9.  Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate.

Authors:  J V Virbasius; X Song; D P Pomerleau; Y Zhan; G W Zhou; M P Czech
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-23       Impact factor: 11.205

10.  Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain.

Authors:  Frits M Flesch; Jong W Yu; Mark A Lemmon; Koert N J Burger
Journal:  Biochem J       Date:  2005-07-15       Impact factor: 3.857
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