Literature DB >> 11280080

Genetic counselling for schizophrenia in the era of molecular genetics.

K A Hodgkinson1, J Murphy, S O'Neill, L Brzustowicz, A S Bassett.   

Abstract

OBJECTIVE: To review the role of genetic counselling for individuals with psychiatric illnesses.
METHOD: Using schizophrenia as an example and including updated information about a genetic subtype (22q deletion syndrome), we discuss the value of the genetic counselling process in psychiatry, with support from the literature and our clinical experience.
RESULTS: Genetic counselling, the process through which knowledge about the genetics of illnesses is shared, provides information on the inheritance of illnesses and their recurrence risks; addresses the concerns of patients, their families, and their health care providers; and supports patients and their families dealing with these illnesses. For comprehensive medical management, this service should be available to all individuals with schizophrenia and their families.
CONCLUSIONS: New findings in the genetics of psychiatric illness may have important clinical implications for patients and their families.

Entities:  

Mesh:

Year:  2001        PMID: 11280080      PMCID: PMC3276586          DOI: 10.1177/070674370104600202

Source DB:  PubMed          Journal:  Can J Psychiatry        ISSN: 0706-7437            Impact factor:   4.356


  84 in total

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Journal:  Nat Genet       Date:  1995-11       Impact factor: 38.330

Review 7.  Investigation of Turner syndrome in schizophrenia.

Authors:  T I Prior; P S Chue; P Tibbo
Journal:  Am J Med Genet       Date:  2000-06-12

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Journal:  Genet Test       Date:  1999

9.  Long term mental illness in Canada: an epidemiological perspective on schizophrenia and affective disorders.

Authors:  R C Bland
Journal:  Can J Psychiatry       Date:  1984-04       Impact factor: 4.356

10.  Duration of psychosis and outcome in first-episode schizophrenia.

Authors:  A D Loebel; J A Lieberman; J M Alvir; D I Mayerhoff; S H Geisler; S R Szymanski
Journal:  Am J Psychiatry       Date:  1992-09       Impact factor: 18.112

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  22 in total

Review 1.  Genetic insights into schizophrenia.

Authors:  A S Bassett; E W Chow; D M Waterworth; L Brzustowicz
Journal:  Can J Psychiatry       Date:  2001-03       Impact factor: 4.356

2.  Clinically detectable copy number variations in a Canadian catchment population of schizophrenia.

Authors:  Anne S Bassett; Gregory Costain; Wai Lun Alan Fung; Kathryn J Russell; Laura Pierce; Ronak Kapadia; Ronald F Carter; Eva W C Chow; Pamela J Forsythe
Journal:  J Psychiatr Res       Date:  2010-11       Impact factor: 4.791

Review 3.  Ethics and neuropsychiatric genetics: a review of major issues.

Authors:  Steven K Hoge; Paul S Appelbaum
Journal:  Int J Neuropsychopharmacol       Date:  2012-01-25       Impact factor: 5.176

4.  The Efficacy of Genetic Counseling for Psychiatric Disorders: a Meta-Analysis.

Authors:  Ramona Moldovan; Sebastian Pintea; Jehannine Austin
Journal:  J Genet Couns       Date:  2017-06-14       Impact factor: 2.537

5.  Clinical features of 78 adults with 22q11 Deletion Syndrome.

Authors:  Anne S Bassett; Eva W C Chow; Janice Husted; Rosanna Weksberg; Oana Caluseriu; Gary D Webb; Michael A Gatzoulis
Journal:  Am J Med Genet A       Date:  2005-11-01       Impact factor: 2.802

6.  Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior.

Authors:  Avanti Gokhale; Cortnie Hartwig; Amanda A H Freeman; Julia L Bassell; Stephanie A Zlatic; Christie Sapp Savas; Trishna Vadlamudi; Farida Abudulai; Tyler T Pham; Amanda Crocker; Erica Werner; Zhexing Wen; Gabriela M Repetto; Joseph A Gogos; Steven M Claypool; Jennifer K Forsyth; Carrie E Bearden; Jill Glausier; David A Lewis; Nicholas T Seyfried; Jennifer Q Kwong; Victor Faundez
Journal:  J Neurosci       Date:  2019-03-04       Impact factor: 6.167

7.  Evaluating genetic counseling for family members of individuals with schizophrenia in the molecular age.

Authors:  Gregory Costain; Mary Jane Esplen; Brenda Toner; Kathleen A Hodgkinson; Anne S Bassett
Journal:  Schizophr Bull       Date:  2012-10-27       Impact factor: 9.306

8.  Evaluating genetic counseling for individuals with schizophrenia in the molecular age.

Authors:  Gregory Costain; Mary Jane Esplen; Brenda Toner; Stephen W Scherer; Wendy S Meschino; Kathleen A Hodgkinson; Anne S Bassett
Journal:  Schizophr Bull       Date:  2012-12-12       Impact factor: 9.306

Review 9.  Schizophrenia and genetics: new insights.

Authors:  Anne S Bassett; Eva W Chow; Rosanna Weksberg; Linda Brzustowicz
Journal:  Curr Psychiatry Rep       Date:  2002-08       Impact factor: 5.285

10.  Psychiatric disorders in clinical genetics II: Individualizing recurrence risks.

Authors:  Jehannine C Austin; Christina G S Palmer; Beth Rosen-Sheidley; Patricia McCarthy Veach; Elizabeth Gettig; Holly L Peay
Journal:  J Genet Couns       Date:  2007-12-11       Impact factor: 2.537

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