| Literature DB >> 11277769 |
A M Galal1, E A Abourashed, S A Ross, M A ElSohly, M S Al-Said, F S El-Feraly.
Abstract
The roots of Ferula hermonis Boiss yielded two new daucane esters, 14-(4'-hydroxybenzoyloxy)dauc-4,8-diene (1) and 14-(4'-hydroxy-3'-methoxybenzoyloxy)dauc-4,8-diene (2), together with the four known sesquiterpenes jaeschkeanadiol p-hydroxybenzoate (3), jaeschkeanadiol benzoate (4), jaeschkeanadiol (5), and epoxyjaeschkeanadiol (6). The identities of the isolated compounds were ascertained primarily using NMR and MS data. Compounds 1 and 3 exhibited antimicrobial activity against Staphylococcus aureus with IC(50) 1.5 and 3.5 microg/mL, respectively, and against Methicillin-resistant S. aureus with IC(50) 2.0 and 4.0 microg/mL, respectively.Entities:
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Year: 2001 PMID： 11277769 DOI： 10.1021/np000526x
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050