Literature DB >> 11185405

Origin of life. A simpler nucleic acid.

L Orgel1.   

Abstract

What was the genetic material of the earliest life forms on Earth if it was not RNA? As Orgel explains in his Perspective, the answer may be simpler nucleic acid polymers perhaps like the RNA analogs called (L)-a-threofuranosyl oligonucleotides or TNAs (Schöning et al.). These molecules have threose rather than ribose in their sugar-phosphate backbones and yet retain many of the properties of RNA including the ability to pair up in double helices.

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Year:  2000        PMID: 11185405     DOI: 10.1126/science.290.5495.1306

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  22 in total

1.  The TNA-family of nucleic acid systems: properties and prospects.

Authors:  Albert Eschenmoser
Journal:  Orig Life Evol Biosph       Date:  2004-06       Impact factor: 1.950

2.  Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor.

Authors:  Hanyang Yu; Su Zhang; John C Chaput
Journal:  Nat Chem       Date:  2012-01-10       Impact factor: 24.427

3.  Homochiral selectivity in RNA synthesis: montmorillonite-catalyzed quaternary reactions of D, L-purine with D, L- pyrimidine nucleotides.

Authors:  Prakash C Joshi; Michael F Aldersley; James P Ferris
Journal:  Orig Life Evol Biosph       Date:  2010-08-20       Impact factor: 1.950

4.  Conditions for the emergence of life on the early Earth: summary and reflections.

Authors:  Joshua Jortner
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-10-29       Impact factor: 6.237

Review 5.  The algorithmic origins of life.

Authors:  Sara Imari Walker; Paul C W Davies
Journal:  J R Soc Interface       Date:  2012-12-12       Impact factor: 4.118

6.  Modulation of adenosine 5'-monophosphate adsorption onto aqueous resident pyrite: potential mechanisms for prebiotic reactions.

Authors:  M Pontes-Buarques; A C Tessis; J A Bonapace; M B Monte; G Cortés-Lopez; F De Souza-Barros; A Vieyra
Journal:  Orig Life Evol Biosph       Date:  2001 Aug-Oct       Impact factor: 1.950

Review 7.  Coenzyme world model of the origin of life.

Authors:  Alexei A Sharov
Journal:  Biosystems       Date:  2016-03-09       Impact factor: 1.973

Review 8.  Primitive genetic polymers.

Authors:  Aaron E Engelhart; Nicholas V Hud
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-05-12       Impact factor: 10.005

9.  Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes.

Authors:  Irina Anosova; Ewa A Kowal; Nicholas J Sisco; Sujay Sau; Jen-Yu Liao; Saikat Bala; Eriks Rozners; Martin Egli; John C Chaput; Wade D Van Horn
Journal:  Chembiochem       Date:  2016-07-29       Impact factor: 3.164

10.  Significance of mineral salts in prebiotic RNA synthesis catalyzed by montmorillonite.

Authors:  Prakash C Joshi; Michael F Aldersley
Journal:  J Mol Evol       Date:  2013-06-18       Impact factor: 2.395

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