Literature DB >> 11183758

Drugs. Reinventing an ancient cure for malaria.

E Marshall.   

Abstract

As drug resistance renders cheap antimalarials ineffective, a promising candidate has emerged from an overlooked source: Asia. Used as herbal remedies in China for 2000 years, artemisinins haven't yet been approved for clinical use in Western countries. But abundant clinical data show that a water-soluble form called artesunate knocks down the number of parasites in the blood faster than any other drug does.

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Year:  2000        PMID: 11183758     DOI: 10.1126/science.290.5491.437

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Antimalarial activity of a new family of analogues of manzamine A.

Authors:  Jeffrey D Winkler; Allyn T Londregan; Mark T Hamann
Journal:  Org Lett       Date:  2006-06-08       Impact factor: 6.005

2.  Synthesis and biological evaluation of manzamine analogues.

Authors:  Jeffrey D Winkler; Allyn T Londregan; Justin R Ragains; Mark T Hamann
Journal:  Org Lett       Date:  2006-07-20       Impact factor: 6.005

  2 in total

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