Literature DB >> 11173046

Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs.

S Hernández-Díaz1, L A García-Rodríguez.   

Abstract

The use of conventional nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with upper gastrointestinal bleeding and perforation (UGIB), acute liver injury, acute renal injury, heart failure, and adverse reproductive outcomes. This article summarizes the effects of various factors, such as NSAID dose, duration of treatment, patient age, and ulcer history, on the incidences of these adverse side effects. We used the UK General Practice Research Database to study further the principal safety concern related to NSAIDs, namely, UGIB.

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Year:  2001        PMID： 11173046     DOI： 10.1016/s0002-9343(00)00682-3

Source DB:  PubMed          Journal:  Am J Med        ISSN： 0002-9343            Impact factor:   4.965


  37 in total

1.  Analytic strategies to adjust confounding using exposure propensity scores and disease risk scores: nonsteroidal antiinflammatory drugs and short-term mortality in the elderly.

Authors:  Til Stürmer; Sebastian Schneeweiss; M Alan Brookhart; Kenneth J Rothman; Jerry Avorn; Robert J Glynn
Journal:  Am J Epidemiol       Date:  2005-05-01       Impact factor: 4.897

2.  Adjusting effect estimates for unmeasured confounding with validation data using propensity score calibration.

Authors:  Til Stürmer; Sebastian Schneeweiss; Jerry Avorn; Robert J Glynn
Journal:  Am J Epidemiol       Date:  2005-06-29       Impact factor: 4.897

Review 3.  Self-management strategies to reduce pain and improve function among older adults in community settings: a review of the evidence.

Authors:  M Carrington Reid; Maria Papaleontiou; Anthony Ong; Risa Breckman; Elaine Wethington; Karl Pillemer
Journal:  Pain Med       Date:  2008-03-11       Impact factor: 3.750

Review 4.  Single dose oral diclofenac for acute postoperative pain in adults.

Authors:  Philip Derry; Sheena Derry; R Andrew Moore; Henry J McQuay
Journal:  Cochrane Database Syst Rev       Date:  2009-04-15

5.  Nonsteroidal anti-inflammatory drugs for rheumatoid arthritis during pregnancy.

Authors:  Ana Florescu; Gideon Koren
Journal:  Can Fam Physician       Date:  2005-07       Impact factor: 3.275

6.  A cognitive-behavioral plus exercise intervention for older adults with chronic back pain: race/ethnicity effect?

Authors:  Katherine Beissner; Samantha J Parker; Charles R Henderson; Anusmiriti Pal; Lynne Iannone; M Cary Reid
Journal:  J Aging Phys Act       Date:  2011-10-18       Impact factor: 1.961

Review 7.  Single dose oral ibuprofen for acute postoperative pain in adults.

Authors:  Christopher Derry; Sheena Derry; R Andrew Moore; Henry J McQuay
Journal:  Cochrane Database Syst Rev       Date:  2009-07-08

8.  Pharmacokinetic-pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in rats.

Authors:  D A Vásquez-Bahena; U E Salazar-Morales; M I Ortiz; G Castañeda-Hernández; Iñaki F Trocóniz
Journal:  Br J Pharmacol       Date:  2009-12-02       Impact factor: 8.739

9.  Cohort study of hepatotoxicity associated with nimesulide and other non-steroidal anti-inflammatory drugs.

Authors:  Giuseppe Traversa; Clara Bianchi; Roberto Da Cas; Iosief Abraha; Francesca Menniti-Ippolito; Mauro Venegoni
Journal:  BMJ       Date:  2003-07-05

Review 10.  Single dose oral diclofenac for acute postoperative pain in adults.

Authors:  Sheena Derry; Philip J Wiffen; R Andrew Moore
Journal:  Cochrane Database Syst Rev       Date:  2015-07-07
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