Further information on the knowledge of topographical corneal thickness.

Central and peripheral corneal thickness has been used increasingly to obtain information about physiologic and clinical conditions of the cornea. In this study, a new method based on ultrasonic pachometry for topographical corneal thickness measurement is described. Results suggest that the technique is reliable for clinical determination of global corneal thickness. Measurements taken by one observer on different sessions (intersession variation) and measurements taken by different observers (interobserver variation) are not significant different (p = 0.586 and 0.273, respectively). This new ultrasound topographical pachometric method can be considered a useful tool for determination of topographical corneal thickness. It has implications for the use of topographical ultrasonic pachometry in contact lenses research, refractive surgery, and management of different pathologic conditions.