Literature DB >> 11163153

Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?

K Labib1, J F Diffley.   

Abstract

The MCM2-7 complex is essential for both the initiation and elongation phases of eukaryotic chromosome replication. There is some evidence that MCM2-7 proteins may act as a DNA helicase; at the same time, a variety of other DNA helicases have also been implicated in the replication of eukaryotic chromosomes.

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Year:  2001        PMID： 11163153     DOI： 10.1016/s0959-437x(00)00158-1

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  60 in total

1.  Essential role of MCM proteins in premeiotic DNA replication.

Authors:  Karola Lindner; Juraj Gregán; Stuart Montgomery; Stephen E Kearsey
Journal:  Mol Biol Cell       Date:  2002-02       Impact factor: 4.138

2.  Minichromosome maintenance (MCM) proteins may be pre-cancer markers.

Authors:  M R Alison; T Hunt; S J Forbes
Journal:  Gut       Date:  2002-03       Impact factor: 23.059

3.  RPA is an initiation factor for human chromosomal DNA replication.

Authors:  Dávid Szüts; Lisa Kitching; Christo Christov; Aidan Budd; Sew Peak-Chew; Torsten Krude
Journal:  Nucleic Acids Res       Date:  2003-03-15       Impact factor: 16.971

4.  Hexameric ring structure of the full-length archaeal MCM protein complex.

Authors:  Tillmann Pape; Hedije Meka; Shaoxia Chen; Giorgia Vicentini; Marin van Heel; Silvia Onesti
Journal:  EMBO Rep       Date:  2003-10-17       Impact factor: 8.807

5.  Bidirectional DNA unwinding by a ternary complex of T antigen, nucleolin and topoisomerase I.

Authors:  Stephanie Seinsoth; Heike Uhlmann-Schiffler; Hans Stahl
Journal:  EMBO Rep       Date:  2003-03       Impact factor: 8.807

6.  DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.

Authors:  Jennifer A Cobb; Lotte Bjergbaek; Kenji Shimada; Christian Frei; Susan M Gasser
Journal:  EMBO J       Date:  2003-08-15       Impact factor: 11.598

7.  Sequence-independent DNA binding and replication initiation by the human origin recognition complex.

Authors:  Sanjay Vashee; Christin Cvetic; Wenyan Lu; Pamela Simancek; Thomas J Kelly; Johannes C Walter
Journal:  Genes Dev       Date:  2003-08-01       Impact factor: 11.361

8.  MCM proteins and checkpoint kinases get together at the fork.

Authors:  David Shechter; Jean Gautier
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-19       Impact factor: 11.205

9.  A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication.

Authors:  Marcin Pacek; Johannes C Walter
Journal:  EMBO J       Date:  2004-08-26       Impact factor: 11.598

Review 10.  Regulation of the initiation step of DNA replication by cyclin-dependent kinases.

Authors:  Seiji Tanaka; Hiroyuki Araki
Journal:  Chromosoma       Date:  2010-08-05       Impact factor: 4.316
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