K McKenzie1, C Samele, E Van Horn, T Tattan, J Van Os, R Murray. 1. Haringey Healthcare Trust and University Department of Psychiatry, Royal Free and University College Medical Schools, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK.
Abstract
BACKGROUND: The comparative outcome of psychosis in British Whites and UK African-Caribbeans is unclear. Some report that African-Caribbeans have worse outcome, whereas others claim better symptomatic outcome and a more benign course. AIMS: To compare the course, outcome and treatment of psychosis in African-Caribbeans and British Whites in a large multi-centre sample. METHOD: A secondary analysis of 708 patients with research diagnostic criteria-defined psychosis from a 2-year, randomised controlled trial of case management. Outcome measures (hospitalisation, illness course, self-harm, social disability and treatment received) were adjusted for socio-economic and clinical differences between groups at baseline using regression analysis. RESULTS: African-Caribbeans were less likely to have a continuous illness and to receive treatment with antidepressant or psychotherapy. CONCLUSIONS: The outcome of psychosis is complex but differs between UK African-Caribbeans and British Whites. This may reflect risk factors that increase the rate of psychosis in UK African-Caribbeans. Treatment differences require further investigation.
RCT Entities:
BACKGROUND: The comparative outcome of psychosis in British Whites and UK African-Caribbeans is unclear. Some report that African-Caribbeans have worse outcome, whereas others claim better symptomatic outcome and a more benign course. AIMS: To compare the course, outcome and treatment of psychosis in African-Caribbeans and British Whites in a large multi-centre sample. METHOD: A secondary analysis of 708 patients with research diagnostic criteria-defined psychosis from a 2-year, randomised controlled trial of case management. Outcome measures (hospitalisation, illness course, self-harm, social disability and treatment received) were adjusted for socio-economic and clinical differences between groups at baseline using regression analysis. RESULTS: African-Caribbeans were less likely to have a continuous illness and to receive treatment with antidepressant or psychotherapy. CONCLUSIONS: The outcome of psychosis is complex but differs between UK African-Caribbeans and British Whites. This may reflect risk factors that increase the rate of psychosis in UK African-Caribbeans. Treatment differences require further investigation.
Authors: Baptiste Pignon; Franck Schürhoff; Grégoire Baudin; Andrea Tortelli; Aziz Ferchiou; Ghassen Saba; Jean-Romain Richard; Antoine Pelissolo; Marion Leboyer; Andrei Szöke Journal: Int J Methods Psychiatr Res Date: 2018-05-22 Impact factor: 4.035
Authors: Michael King; James Nazroo; Scott Weich; Kwame McKenzie; Kam Bhui; Saffron Karlsen; Saffron Karlson; Stephen Stansfeld; Peter Tyrer; Martin Blanchard; Keith Lloyd; Sally McManus; Kerry Sproston; Bob Erens Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2005-05 Impact factor: 4.328