Literature DB >> 11102863

Synthetically modified DNAs as substrates for polymerases.

E T Kool1.   

Abstract

DNA polymerase enzymes process their natural substrates with very high specificity. Yet recent experiments have shown that these enzymes can also process DNA in which the backbone or bases are modified to a surprising degree. Such experiments have important implications in understanding the mechanisms of DNA replication, and suggest important biotechnological uses as well.

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Year:  2000        PMID： 11102863     DOI： 10.1016/s1367-5931(00)00141-1

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  21 in total

1.  Effect of lesions on the dynamics of DNA on the picosecond and nanosecond timescales using a polarity sensitive probe.

Authors:  Mark M Somoza; Daniele Andreatta; Catherine J Murphy; Robert S Coleman; Mark A Berg
Journal:  Nucleic Acids Res       Date:  2004-05-06       Impact factor: 16.971

2.  Importance of steric effects on the efficiency and fidelity of transcription by T7 RNA polymerase.

Authors:  Sébastien Ulrich; Eric T Kool
Journal:  Biochemistry       Date:  2011-11-01       Impact factor: 3.162

3.  Reversible bond formation enables the replication and amplification of a crosslinking salen complex as an orthogonal base pair.

Authors:  Corinna Kaul; Markus Müller; Mirko Wagner; Sabine Schneider; Thomas Carell
Journal:  Nat Chem       Date:  2011-08-28       Impact factor: 24.427

4.  Optimization of unnatural base pair packing for polymerase recognition.

Authors:  Shigeo Matsuda; Allison A Henry; Floyd E Romesberg
Journal:  J Am Chem Soc       Date:  2006-05-17       Impact factor: 15.419

5.  Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis.

Authors:  Yasushi Hikida; Michiko Kimoto; Shigeyuki Yokoyama; Ichiro Hirao
Journal:  Nat Protoc       Date:  2010-06-24       Impact factor: 13.491

Review 6.  Incorporation of nonstandard amino acids into proteins: principles and applications.

Authors:  Tianwen Wang; Chen Liang; Hongjv Xu; Yafei An; Sha Xiao; Mengyuan Zheng; Lu Liu; Lei Nie
Journal:  World J Microbiol Biotechnol       Date:  2020-04-08       Impact factor: 3.312

7.  Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity.

Authors:  Matthew W Kellinger; Sébastien Ulrich; Jenny Chong; Eric T Kool; Dong Wang
Journal:  J Am Chem Soc       Date:  2012-05-02       Impact factor: 15.419

8.  Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.

Authors:  Shigeo Matsuda; Jeremiah D Fillo; Allison A Henry; Priyamrada Rai; Steven J Wilkens; Tammy J Dwyer; Bernhard H Geierstanger; David E Wemmer; Peter G Schultz; Glen Spraggon; Floyd E Romesberg
Journal:  J Am Chem Soc       Date:  2007-08-08       Impact factor: 15.419

Review 9.  Artificial genetic sets composed of size-expanded base pairs.

Authors:  Malte Winnacker; Eric T Kool
Journal:  Angew Chem Int Ed Engl       Date:  2013-11-07       Impact factor: 15.336

10.  Highly specific unnatural base pair systems as a third base pair for PCR amplification.

Authors:  Rie Yamashige; Michiko Kimoto; Yusuke Takezawa; Akira Sato; Tsuneo Mitsui; Shigeyuki Yokoyama; Ichiro Hirao
Journal:  Nucleic Acids Res       Date:  2011-11-24       Impact factor: 16.971
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