Literature DB >> 11089980

Why do we age?

T B Kirkwood1, S N Austad.   

Abstract

The evolutionary theory of ageing explains why ageing occurs, giving valuable insight into the mechanisms underlying the complex cellular and molecular changes that contribute to senescence. Such understanding also helps to clarify how the genome shapes the ageing process, thereby aiding the study of the genetic factors that influence longevity and age-associated diseases.

Mesh：

Year:  2000        PMID： 11089980     DOI： 10.1038/35041682

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  400 in total

1.  Division of labour influences the rate of ageing in weaver ant workers.

Authors:  Michel Chapuisat; Laurent Keller
Journal:  Proc Biol Sci       Date:  2002-05-07       Impact factor: 5.349

2.  Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies.

Authors:  James H Marden; Blanka Rogina; Kristi L Montooth; Stephen L Helfand
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-07       Impact factor: 11.205

3.  A test of evolutionary theories of aging.

Authors:  Kimberly A Hughes; Julie A Alipaz; Jenny M Drnevich; Rose M Reynolds
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-17       Impact factor: 11.205

Review 4.  How long should telomeres be?

Authors:  A Aviv; C B Harley
Journal:  Curr Hypertens Rep       Date:  2001-04       Impact factor: 5.369

5.  High sexual signalling rates of young individuals predict extended life span in male Mediterranean fruit flies.

Authors:  Nikos T Papadopoulos; Byron I Katsoyannos; Nikos A Kouloussis; James R Carey; Hans-Georg Müller; Ying Zhang
Journal:  Oecologia       Date:  2003-10-24       Impact factor: 3.225

Review 6.  Molecular gerontology.

Authors:  T B L Kirkwood
Journal:  J Inherit Metab Dis       Date:  2002-05       Impact factor: 4.982

Review 7.  From genes to societies.

Authors:  Olav Rueppell; Gro V Amdam; Robert E Page; James R Carey
Journal:  Sci Aging Knowledge Environ       Date:  2004-02-04

8.  The most pressing problem of our age.

Authors:  Thomas B L Kirkwood
Journal:  BMJ       Date:  2003-06-14

9.  An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster.

Authors:  Johannes H Bauer; Stephan Goupil; Graham B Garber; Stephen L Helfand
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-24       Impact factor: 11.205

10.  Construction of an integral formula of biological age for a healthy Chinese population using principle component analysis.

Authors:  W-G Zhang; X-J Bai; X-F Sun; G-Y Cai; X-Y Bai; S-Y Zhu; M Zhang; X-M Chen
Journal:  J Nutr Health Aging       Date:  2014       Impact factor: 4.075
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