BACKGROUND AND OBJECTIVES: We investigated the relationship between peritoneal metastasis and lymphatic involvement in gastric cancer by examining resected specimens. METHODS: Twenty-seven consecutive gastric cancer patients who had synchronous peritoneal metastasis and 29 who developed metachronous peritoneal metastasis after surgery between 1985 and 1997 were included in this study. They were compared with 61 advanced gastric cancer (pT2 or more deeply into the gastric wall in the UICC-TNM) patients who had neither synchronous nor subsequent peritoneal metastasis, and who lived a disease-free course during 3 years. We compared the patients' clinico-pathological features and in particular, the patterns of extranodal invasion in the resected lymph nodes. RESULTS: Extranodal invasion with peritoneal metastasis was more common than extranodal invasion without peritoneal metastasis (P < 0.0001). Multivariate analysis revealed that the correlation between extranodal invasion and peritoneal metastasis was highly significant (P < 0.0001); the odds ratio was 18.894. Metastasis to the lymph nodes was the next most significant risk for peritoneal metastasis (P = 0.0043). CONCLUSIONS: We believe that the lymphatic system correlates closely with the establishment of peritoneal metastasis. Copyright 2000 Wiley-Liss, Inc.
BACKGROUND AND OBJECTIVES: We investigated the relationship between peritoneal metastasis and lymphatic involvement in gastric cancer by examining resected specimens. METHODS: Twenty-seven consecutive gastric cancerpatients who had synchronous peritoneal metastasis and 29 who developed metachronous peritoneal metastasis after surgery between 1985 and 1997 were included in this study. They were compared with 61 advanced gastric cancer (pT2 or more deeply into the gastric wall in the UICC-TNM) patients who had neither synchronous nor subsequent peritoneal metastasis, and who lived a disease-free course during 3 years. We compared the patients' clinico-pathological features and in particular, the patterns of extranodal invasion in the resected lymph nodes. RESULTS: Extranodal invasion with peritoneal metastasis was more common than extranodal invasion without peritoneal metastasis (P < 0.0001). Multivariate analysis revealed that the correlation between extranodal invasion and peritoneal metastasis was highly significant (P < 0.0001); the odds ratio was 18.894. Metastasis to the lymph nodes was the next most significant risk for peritoneal metastasis (P = 0.0043). CONCLUSIONS: We believe that the lymphatic system correlates closely with the establishment of peritoneal metastasis. Copyright 2000 Wiley-Liss, Inc.
Authors: Nicola Veronese; Matteo Fassan; Laura D Wood; Brendon Stubbs; Marco Solmi; Paola Capelli; Antonio Pea; Alessia Nottegar; Giuseppe Sergi; Enzo Manzato; Sara Carraro; Marco Maruzzo; Ivana Cataldo; Fabio Bagante; Mattia Barbareschi; Liang Cheng; Maria Bencivenga; Giovanni de Manzoni; Claudio Luchini Journal: J Gastrointest Surg Date: 2016-07-13 Impact factor: 3.452
Authors: Peter C Ambe; Daniel Gödde; Stephan Störkel; Hubert Zirngibl; Lars Bönicke Journal: Int J Colorectal Dis Date: 2018-03-08 Impact factor: 2.571