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Literature DB >> 11073931

Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae.

Abstract

In the peptidoglycan of Mycobacterium leprae, L-alanine of the side chain is replaced by glycine. When expressed in Escherichia coli, MurC (UDP-N-acetyl-muramate:L-alanine ligase) of M. leprae showed K(m) and V(max) for L-alanine and glycine similar to those of Mycobacterium tuberculosis MurC, suggesting that another explanation should be sought for the presence of glycine.

Entities: Chemical Disease Species

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Year: 2000 PMID： 11073931 PMCID： PMC111429 DOI： 10.1128/JB.182.23.6827-6830.2000

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

16 in total

1. Preparation of clinical grade proteins produced by recombinant DNA technologies.

Authors: B J Takacs; M F Girard
Journal: J Immunol Methods Date: 1991-10-25 Impact factor: 2.303

2. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

3. Peptidoglycan and arabinogalactan of Mycobacterium leprae.

Authors: P Draper; O Kandler; A Darbre
Journal: J Gen Microbiol Date: 1987-05

4. Cloning and sequencing of Staphylococcus aureus murC, a gene essential for cell wall biosynthesis.

Authors: A M Lowe; R L Deresiewicz
Journal: DNA Seq Date: 1999

5. The division and cell wall gene cluster of Enterococcus hirae S185.

Authors: C Duez; I Thamm; F Sapunaric; J Coyette; J M Ghuysen
Journal: DNA Seq Date: 1998

6. Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase.

Authors: J J Emanuele; H Jin; B L Jacobson; C Y Chang; H M Einspahr; J J Villafranca
Journal: Protein Sci Date: 1996-12 Impact factor: 6.725

Review 7. The envelope of mycobacteria.

Authors: P J Brennan; H Nikaido
Journal: Annu Rev Biochem Date: 1995 Impact factor: 23.643

8. Over-production, purification and properties of the uridine-diphosphate-N-acetylmuramate:L-alanine ligase from Escherichia coli.

Authors: D Liger; A Masson; D Blanot; J van Heijenoort; C Parquet
Journal: Eur J Biochem Date: 1995-05-15

9. Structural studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase.

Authors: H Jin; J J Emanuele; R Fairman; J G Robertson; M E Hail; H T Ho; P J Falk; J J Villafranca
Journal: Biochemistry Date: 1996-02-06 Impact factor: 3.162

10. A murC gene in Porphyromonas gingivalis 381.

Authors: T Ansai; Y Yamashita; S Awano; Y Shibata; M Wachi; K Nagai; T Takehara
Journal: Microbiology Date: 1995-09 Impact factor: 2.777

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Journal: J Mol Model Date: 2011-04-15 Impact factor: 1.810

Review 2. Targeting the formation of the cell wall core of M. tuberculosis.

Authors: Clifton E Barry; Dean C Crick; Michael R McNeil
Journal: Infect Disord Drug Targets Date: 2007-06

Review 3. The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.

Authors: Luke J Alderwick; James Harrison; Georgina S Lloyd; Helen L Birch
Journal: Cold Spring Harb Perspect Med Date: 2015-03-27 Impact factor: 6.915

4. Defining mycobacteria: Shared and specific genome features for different lifestyles.

Authors: Varalakshmi D Vissa; Rama Murthy Sakamuri; Wei Li; Patrick J Brennan
Journal: Indian J Microbiol Date: 2009-02-05 Impact factor: 2.461

5. Structural characterization of muropeptides from Chlamydia trachomatis peptidoglycan by mass spectrometry resolves "chlamydial anomaly".

Authors: Mathanraj Packiam; Brian Weinrick; William R Jacobs; Anthony T Maurelli
Journal: Proc Natl Acad Sci U S A Date: 2015-08-19 Impact factor: 11.205

6. Homology modeling and docking analyses of M. leprae Mur ligases reveals the common binding residues for structure based drug designing to eradicate leprosy.

Authors: Anusuya Shanmugam; Jeyakumar Natarajan
Journal: J Mol Model Date: 2011-11-19 Impact factor: 1.810

7. Functional and biochemical analysis of Chlamydia trachomatis MurC, an enzyme displaying UDP-N-acetylmuramate:amino acid ligase activity.

Authors: Lars Hesse; Julieanne Bostock; Sebastien Dementin; Didier Blanot; Dominique Mengin-Lecreulx; Ian Chopra
Journal: J Bacteriol Date: 2003-11 Impact factor: 3.490