M E Parent1, Y Hua, J Siemiatycki. 1. INRS-Institut Armand-Frappier, Laval, Quebec, Canada. marie-elise.parent@inrs-iaf.uquebec.ca
Abstract
BACKGROUND: Little is known about the role of workplace exposures on the risk of renal cell cancer. METHODS: A population-based case-control study was undertaken in Montreal to assess the association between hundreds of occupational circumstances and several cancer sites, including the kidney. A total of 142 male patients with pathologically confirmed renal cell carcinoma, 1900 controls with cancer at other sites and 533 population-based controls were interviewed. Detailed job histories and relevant data on potential confounders were obtained. A group of chemists-hygienists evaluated each job reported and translated them into a history of occupational exposures using a checklist of 294 substances. Multivariate logistic regression models using either population, cancer controls, or a pool of both groups were used to estimate odds ratios. RESULTS: There were some indications of excess risks among printers, nursery workers (gardening), aircraft mechanics, farmers, and horticulturists, as well as in the following industries: printing-related services, defense services, wholesale trade, and retail trade. Notwithstanding the low precision of many of the odds ratio estimates, the following workplace exposures showed some evidence of excess risk: chromium compounds, chromium (VI) compounds, inorganic acid solutions, styrene-butadiene rubber, ozone, hydrogen sulphide, ultraviolet radiation, hair dust, felt dust, jet fuel engine emissions, jet fuel, aviation gasoline, phosphoric acid and inks. CONCLUSIONS: For most of these associations there exist no, or very little, previous data. Some associations provide suggestive evidence for further studies. Copyright 2000 Wiley-Liss, Inc.
BACKGROUND: Little is known about the role of workplace exposures on the risk of renal cell cancer. METHODS: A population-based case-control study was undertaken in Montreal to assess the association between hundreds of occupational circumstances and several cancer sites, including the kidney. A total of 142 male patients with pathologically confirmed renal cell carcinoma, 1900 controls with cancer at other sites and 533 population-based controls were interviewed. Detailed job histories and relevant data on potential confounders were obtained. A group of chemists-hygienists evaluated each job reported and translated them into a history of occupational exposures using a checklist of 294 substances. Multivariate logistic regression models using either population, cancer controls, or a pool of both groups were used to estimate odds ratios. RESULTS: There were some indications of excess risks among printers, nursery workers (gardening), aircraft mechanics, farmers, and horticulturists, as well as in the following industries: printing-related services, defense services, wholesale trade, and retail trade. Notwithstanding the low precision of many of the odds ratio estimates, the following workplace exposures showed some evidence of excess risk: chromium compounds, chromium (VI) compounds, inorganic acid solutions, styrene-butadiene rubber, ozone, hydrogen sulphide, ultraviolet radiation, hair dust, felt dust, jet fuel engine emissions, jet fuel, aviation gasoline, phosphoric acid and inks. CONCLUSIONS: For most of these associations there exist no, or very little, previous data. Some associations provide suggestive evidence for further studies. Copyright 2000 Wiley-Liss, Inc.
Authors: Sara Karami; Paolo Boffetta; Paul Brennan; Patricia A Stewart; David Zaridze; Vsevolod Matveev; Vladimir Janout; Helena Kollarova; Vladimir Bencko; Marie Navratilova; Neonila Szeszenia-Dabrowska; Dana Mates; Jan P Gromiec; Roman Sobotka; Wong-Ho Chow; Nathaniel Rothman; Lee E Moore Journal: J Occup Environ Med Date: 2011-02 Impact factor: 2.162
Authors: J E Heck; B Charbotel; L E Moore; S Karami; D G Zaridze; V Matveev; V Janout; H Kollárová; L Foretova; V Bencko; N Szeszenia-Dabrowska; J Lissowska; D Mates; G Ferro; W-H Chow; N Rothman; P Stewart; P Brennan; P Boffetta Journal: Occup Environ Med Date: 2009-09-07 Impact factor: 4.402
Authors: L Buzio; G De Palma; P Mozzoni; M Tondel; C Buzio; I Franchini; O Axelson; A Mutti Journal: Occup Environ Med Date: 2003-10 Impact factor: 4.402
Authors: Sara Karami; Joanne S Colt; Kendra Schwartz; Faith G Davis; Julie J Ruterbusch; Stella S Munuo; Sholom Wacholder; Patricia A Stewart; Barry I Graubard; Nathanial Rothman; Wong-Ho Chow; Mark P Purdue Journal: BMC Cancer Date: 2012-08-08 Impact factor: 4.430