Literature DB >> 11064398

Gd-DTPA relaxivity depends on macromolecular content.

G J Stanisz1, R M Henkelman.   

Abstract

Gd-DTPA T(1) relaxivity of water protons was measured at 1.5 T and room temperature as a function of macromolecular content in model systems. Gd-DTPA relaxivity was found to increase with macromolecular concentration. The results of this study indicate that the Gd-DTPA relaxivity in tissue extracellular compartment could be as much as 30-70% higher than that of Gd-DTPA in saline. Quantitative MR analyses that use T(1) as an estimation of local Gd-DTPA concentration require a priori determination of the Gd relaxivity in tissue.

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Year:  2000        PMID： 11064398     DOI： 10.1002/1522-2594(200011)44:5<665::aid-mrm1>3.0.co;2-m

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  48 in total

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