Literature DB >> 11060645

Salt-induced DNA-histone complexation.

K K Kunze1, R R Netz.   

Abstract

We study numerically the binding of one semiflexible charged polymer onto an oppositely charged sphere. Using parameters appropriate for DNA-histone complexes, we find complete wrapping for intermediate salt concentrations only, in agreement with experiments. For high salt concentrations, a strongly discontinuous dewrapping occurs. For low salt concentrations, we find multiple conformational transitions, leading to an extended DNA configuration. The wrapped states are characterized by spontaneously broken rotational and mirror symmetries, giving rise to four distinct structures.

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Year:  2000        PMID: 11060645     DOI: 10.1103/PhysRevLett.85.4389

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  16 in total

1.  A statistical thermodynamic model applied to experimental AFM population and location data is able to quantify DNA-histone binding strength and internucleosomal interaction differences between acetylated and unacetylated nucleosomal arrays.

Authors:  F J Solis; R Bash; J Yodh; S M Lindsay; D Lohr
Journal:  Biophys J       Date:  2004-09-03       Impact factor: 4.033

2.  Charge state of the globular histone core controls stability of the nucleosome.

Authors:  Andrew T Fenley; David A Adams; Alexey V Onufriev
Journal:  Biophys J       Date:  2010-09-08       Impact factor: 4.033

3.  Electrophoresis of positioned nucleosomes.

Authors:  Martin Castelnovo; Sébastian Grauwin
Journal:  Biophys J       Date:  2007-02-02       Impact factor: 4.033

4.  Elasticity of DNA and the effect of dendrimer binding.

Authors:  Santosh Mogurampelly; Bidisha Nandy; Roland R Netz; Prabal K Maiti
Journal:  Eur Phys J E Soft Matter       Date:  2013-06-28       Impact factor: 1.890

5.  Structural transitions of encapsidated polyelectrolytes.

Authors:  D G Angelescu; P Linse; T T Nguyen; R F Bruinsma
Journal:  Eur Phys J E Soft Matter       Date:  2008-04-03       Impact factor: 1.890

6.  Label-free detection of DNA hybridization with a compact LSPR-based fiber-optic sensor.

Authors:  Savannah Kaye; Zheng Zeng; Mollye Sanders; Krishnan Chittur; Paula M Koelle; Robert Lindquist; Upender Manne; Yongbin Lin; Jianjun Wei
Journal:  Analyst       Date:  2017-05-15       Impact factor: 4.616

7.  Rigid-body molecular dynamics of DNA inside a nucleosome.

Authors:  Arman Fathizadeh; Azim Berdy Besya; Mohammad Reza Ejtehadi; Helmut Schiessel
Journal:  Eur Phys J E Soft Matter       Date:  2013-03-13       Impact factor: 1.890

8.  Global analysis of the ground-state wrapping conformation of a charged polymer on an oppositely charged nano-sphere.

Authors:  Hoda Boroudjerdi; Ali Naji; A Naji; R Netz
Journal:  Eur Phys J E Soft Matter       Date:  2014-03-31       Impact factor: 1.890

9.  Tuning DNA Condensation with Zwitterionic Polyamidoamine (zPAMAM) Dendrimers.

Authors:  Min An; Gulen Yesilbag Tonga; Sean R Parkin; Vincent M Rotello; Jason E DeRouchey
Journal:  Macromolecules       Date:  2017-10-09       Impact factor: 5.985

10.  Physicochemical and biological properties of self-assembled antisense/poly(amidoamine) dendrimer nanoparticles: the effect of dendrimer generation and charge ratio.

Authors:  Alireza Nomani; Ismaeil Haririan; Ramin Rahimnia; Shamileh Fouladdel; Tarane Gazori; Rassoul Dinarvand; Yadollah Omidi; Ebrahim Azizi
Journal:  Int J Nanomedicine       Date:  2010-05-13
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