BACKGROUND:Radiofrequency catheter ablation within the tricuspid annulus-inferior caval vein isthmus can cure typical atrial flutter. The target for ablation, nonetheless, is relatively wide, and standard ablation procedures may require significant exposure to radiation. METHODS AND RESULTS: A total of 50 patients (mean age, 58+/-11 years) with typical atrial flutter were prospectively randomized to receive isthmus ablation using conventional fluoroscopy for catheter navigation (group I, n=24) or electromagnetic mapping (group II, n=26). Complete bidirectional isthmus block was verified with double potential mapping. If complete isthmus block could not be achieved after 20 radiofrequency pulses or 25 minutes of fluoroscopy, the patients were switched to the other group. Eight patients from group I (33%) but only 1 patient from group II (4%) were switched. Overall, complete isthmus block was achieved in 47 of 50 patients (94%). The overall fluoroscopy time, including the placement of the diagnostic catheters, was 22.0+/-6.3 minutes in group I and 3.9+/-1.5 minutes in group II (P:<0.0001). The fluoroscopy time needed for isthmus mapping was 17.7+/-6.5 minutes in group I and 0.2+/-0.3 minutes in group II (P:<0.0001). CONCLUSIONS:Electromagnetic mapping during the induction of linear lesions for the ablation of atrial flutter permitted a highly significant reduction in exposure to fluoroscopy while maintaining high efficacy, and it allowed the time required for fluoroscopy to be reduced to levels anticipated for diagnostic electrophysiological studies.
RCT Entities:
BACKGROUND: Radiofrequency catheter ablation within the tricuspid annulus-inferior caval vein isthmus can cure typical atrial flutter. The target for ablation, nonetheless, is relatively wide, and standard ablation procedures may require significant exposure to radiation. METHODS AND RESULTS: A total of 50 patients (mean age, 58+/-11 years) with typical atrial flutter were prospectively randomized to receive isthmus ablation using conventional fluoroscopy for catheter navigation (group I, n=24) or electromagnetic mapping (group II, n=26). Complete bidirectional isthmus block was verified with double potential mapping. If complete isthmus block could not be achieved after 20 radiofrequency pulses or 25 minutes of fluoroscopy, the patients were switched to the other group. Eight patients from group I (33%) but only 1 patient from group II (4%) were switched. Overall, complete isthmus block was achieved in 47 of 50 patients (94%). The overall fluoroscopy time, including the placement of the diagnostic catheters, was 22.0+/-6.3 minutes in group I and 3.9+/-1.5 minutes in group II (P:<0.0001). The fluoroscopy time needed for isthmus mapping was 17.7+/-6.5 minutes in group I and 0.2+/-0.3 minutes in group II (P:<0.0001). CONCLUSIONS: Electromagnetic mapping during the induction of linear lesions for the ablation of atrial flutter permitted a highly significant reduction in exposure to fluoroscopy while maintaining high efficacy, and it allowed the time required for fluoroscopy to be reduced to levels anticipated for diagnostic electrophysiological studies.
Authors: Wilson Kwong; Andrea L Neilson; Christine C Chiu; Gil J Gross; Robert M Hamilton; Luc Soucie; Elizabeth A Stephenson; Joel A Kirsh Journal: J Interv Card Electrophysiol Date: 2011-10-18 Impact factor: 1.900
Authors: David J Sahn; Douglas N Stephens; Jonathan M Cannata; K Shung; Omer Oralkan; Amin Nikoozadeh; B T Pierre Khuri-Yakub; Hien Nguyen; Peter Chen; Aaron M Dentinger; Douglas Wildes; Kai E Thomenius; Aman Mahajan; Kalyanam Shivkumar; Matthew O'Donnell Journal: Conf Proc IEEE Eng Med Biol Soc Date: 2009
Authors: D N Stephens; J Cannata; Ruibin Liu; Jian Zhong Zhao; K K Shung; Hien Nguyen; R Chia; A Dentinger; D Wildes; K E Thomenius; A Mahajan; K Shivkumar; Kang Kim; M O'Donnell; A Nikoozadeh; O Oralkan; P T Khuri-Yakub; D J Sahn Journal: IEEE Trans Ultrason Ferroelectr Freq Control Date: 2008-07 Impact factor: 2.725