Literature DB >> 11042824

An analysis of the effect of age on implantation rates.

S D Spandorfer1, P H Chung, I Kligman, H C Liu, O K Davis, Z Rosenwaks.   

Abstract

PURPOSE: To evaluate implantation rate as a function of age.
METHODS: A total of 1621 consecutive cycles of IVF were evaluated for implantation as a function of age at The New York Hospital/Cornell Medical Center.
RESULTS: An overall implantation rate of 23.3% (1328/5691) was found. The implantation rate as a function of age decreased in a nonlinear fashion. Implantation remained constant until the age of 35 and then decreased in a significantly, linear fashion by 2.77% per year (P < 0.001, R2 = 0.975). A formula to predict implantation rates for a given age was developed: Implantation rate = -119.352 + (9.985 x Age - (0.164 x Age2)).
CONCLUSIONS: We have demonstrated that implantation rates remain constant until the age of 35 at which time a linear decrease of 2.77% per year is observed.

Entities:  

Mesh:

Year:  2000        PMID: 11042824      PMCID: PMC3455393          DOI: 10.1023/a:1009422725434

Source DB:  PubMed          Journal:  J Assist Reprod Genet        ISSN: 1058-0468            Impact factor:   3.412


  12 in total

1.  Reproductive span and rate of reproduction among Hutterite women.

Authors:  C TIETZE
Journal:  Fertil Steril       Date:  1957 Jan-Feb       Impact factor: 7.329

2.  Aneuploidy 16 in human embryos increases significantly with maternal age.

Authors:  C A Benadiva; I Kligman; S Munné
Journal:  Fertil Steril       Date:  1996-08       Impact factor: 7.329

3.  Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility.

Authors:  D Navot; P A Bergh; M A Williams; G J Garrisi; I Guzman; B Sandler; L Grunfeld
Journal:  Lancet       Date:  1991-06-08       Impact factor: 79.321

4.  Female age predicts embryonic implantation after ICSI: a case-controlled study.

Authors:  P Devroey; H Godoy; J Smitz; M Camus; H Tournaye; M P Derde; A Van Steirteghem
Journal:  Hum Reprod       Date:  1996-06       Impact factor: 6.918

5.  Female fecundity as a function of age: results of artificial insemination in 2193 nulliparous women with azoospermic husbands. Federation CECOS.

Authors:  D Schwartz; M J Mayaux
Journal:  N Engl J Med       Date:  1982-02-18       Impact factor: 91.245

6.  The impact of embryo quality on pregnancy outcome in elderly women undergoing in vitro fertilization-embryo transfer (IVF-ET).

Authors:  D Feldberg; J Farhi; D Dicker; J Ashkenazi; M Shelef; J A Goldman
Journal:  J In Vitro Fert Embryo Transf       Date:  1990-10

7.  Oocyte donation in menopausal women.

Authors:  S Antinori; C Versaci; G H Gholami; C Panci; B Caffa
Journal:  Hum Reprod       Date:  1993-09       Impact factor: 6.918

8.  Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities.

Authors:  S Munné; M Alikani; G Tomkin; J Grifo; J Cohen
Journal:  Fertil Steril       Date:  1995-08       Impact factor: 7.329

Review 9.  Female reproductive aging--ovarian and uterine factors.

Authors:  D R Meldrum
Journal:  Fertil Steril       Date:  1993-01       Impact factor: 7.329

10.  Reversing the natural decline in human fertility. An extended clinical trial of oocyte donation to women of advanced reproductive age.

Authors:  M V Sauer; R J Paulson; R A Lobo
Journal:  JAMA       Date:  1992-09-09       Impact factor: 56.272

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  8 in total

1.  Assessment of aneuploidy formation in human blastocysts resulting from donated eggs and the necessity of the embryos for aneuploidy screening.

Authors:  Ghassan Haddad; Maimin Deng; Cassie T Wang; Craig Witz; Daniel Williams; Jason Griffith; Josh Skorupski; Jimmy Gill; Wei-Hua Wang
Journal:  J Assist Reprod Genet       Date:  2015-05-09       Impact factor: 3.412

2.  The significance of serum anti-Müllerian hormone (AMH) levels in patients over age 40 in first IVF treatment.

Authors:  Yoko Tokura; Osamu Yoshino; Sayaka Ogura-Nose; Hiroshi Motoyama; Miyuki Harada; Yutaka Osuga; Yasushi Shimizu; Motohiro Ohara; Takeshi Yorimitsu; Osamu Nishii; Shiro Kozuma; Toshihiro Kawamura
Journal:  J Assist Reprod Genet       Date:  2013-05-03       Impact factor: 3.412

3.  Dynamic measurements of serum inhibin B and estradiol: a predictive evaluation of ovarian response to gonadotrophin stimulation in the early stage of IVF treatment.

Authors:  Ming-fang Miao; He-feng Huang
Journal:  J Zhejiang Univ Sci B       Date:  2009-01       Impact factor: 3.066

4.  Developmental stage on day-5 and fragmentation rate on day-3 can influence the implantation potential of top-quality blastocysts in IVF cycles with single embryo transfer.

Authors:  Tiziana della Ragione; Greta Verheyen; Evangelos G Papanikolaou; Lisbet Van Landuyt; Paul Devroey; Andre Van Steirteghem
Journal:  Reprod Biol Endocrinol       Date:  2007-01-26       Impact factor: 5.211

5.  Does ICSI for in vitro fertilization cause more aneuploid embryos?

Authors:  Xiangli Niu; Jiamin Long; Fangqiang Gong; Weihua Wang
Journal:  Mol Cytogenet       Date:  2020-07-01       Impact factor: 2.009

6.  Growth factors, gene activation, and cell recruitment: From intraovarian condensed platelet cytokines to de novo oocyte development.

Authors:  E Scott Sills; Samuel H Wood
Journal:  J Clin Transl Res       Date:  2022-01-25

7.  Predictive factors of successful pregnancy after assisted reproductive technology in women aged 40 years and older.

Authors:  Akihisa Fujimoto; Toshihiro Fujiwara; Hajime Oishi; Tetsuya Hirata; Tetsu Yano; Yuji Taketani
Journal:  Reprod Med Biol       Date:  2009-07-18

8.  High Aneuploidy Rates Observed in Embryos Derived from Donated Oocytes are Related to Male Aging and High Percentages of Sperm DNA Fragmentation.

Authors:  Javier García-Ferreyra; Daniel Luna; Lucy Villegas; Rocío Romero; Patricia Zavala; Roly Hilario; Julio Dueñas-Chacón
Journal:  Clin Med Insights Reprod Health       Date:  2015-11-11
  8 in total

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