Oocyte donation in menopausal women.

Oocyte donation was performed by in-vitro fertilization and embryo transfer in 82 women. The average age of the patients was 48 years (range 26-60), and 71 were over 40 years old, with an average follicle stimulating hormone (FSH) value of 74 +/- 14 IU and oestradiol concentration of 30 +/- 9 pg/ml. Overall 32 clinical pregnancies were achieved, of which 21 reached term, three are ongoing, and eight were lost (six miscarriages, one abruptio placentae, and one severe gestational proteinuria hypertension in the second trimester). The 21 term pregnancies produced 26 newborns; one patient who had had three embryos replaced delivered triplets and three patients had twins. Before the embryo transfer was performed, the endometrium thickness was accurately determined by vaginal ultrasound probe. The highest number of implanted embryos was reached when the endometrium thickness was 9-12 mm.