Literature DB >> 11033712

Why Sackett's analysis of randomized controlled trials fails, but needn't.

S H Shapiro1, K C Glass.   

Abstract

Keywords:  Biomedical and Behavioral Research

Mesh：

Year:  2000        PMID： 11033712      PMCID： PMC80507     

Source DB:  PubMed          Journal:  CMAJ        ISSN： 0820-3946            Impact factor:   8.262


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  4 in total

1.  Why randomized controlled trials fail but needn't: 1. Failure to gain "coal-face" commitment and to use the uncertainty principle.

Authors:  D L Sackett
Journal:  CMAJ       Date:  2000-05-02       Impact factor: 8.262

2.  For and against: clinical equipoise and not the uncertainty principle is the moral underpinning of the randomised controlled trial.

Authors:  C Weijer; S H Shapiro; K Cranley Glass
Journal:  BMJ       Date:  2000-09-23

3.  Trials: the next 50 years. Large scale randomised evidence of moderate benefits.

Authors:  R Peto; C Baigent
Journal:  BMJ       Date:  1998-10-31

4.  Equipoise and the ethics of clinical research.

Authors:  B Freedman
Journal:  N Engl J Med       Date:  1987-07-16       Impact factor: 91.245
  4 in total
  7 in total

1.  Uncertainty about clinical equipoise. Clinical equipoise and the uncertainty principles both require further scrutiny.

Authors:  F Gifford
Journal:  BMJ       Date:  2001-03-31

2.  Equipoise, a term whose time (if it ever came) has surely gone.

Authors:  D L Sackett
Journal:  CMAJ       Date:  2000-10-03       Impact factor: 8.262

3.  Uncertainty about clinical equipoise.

Authors:  I Shrier
Journal:  CMAJ       Date:  2001-06-26       Impact factor: 8.262

4.  Uncertainty about clinical equipoise.

Authors:  F Rolleston
Journal:  CMAJ       Date:  2001-06-26       Impact factor: 8.262

5.  Uncertainty and the ethics of clinical trials.

Authors:  Sven Ove Hansson
Journal:  Theor Med Bioeth       Date:  2006

Review 6.  Critical care trial design and interpretation: a primer.

Authors:  Jonathan E Sevransky; William Checkley; Greg S Martin
Journal:  Crit Care Med       Date:  2010-09       Impact factor: 7.598

Review 7.  Is "rescue" therapy ethical in randomized controlled trials?

Authors:  Richard Holubkov; J Michael Dean; John Berger; Kanwaljeet J S Anand; Joseph Carcillo; Kathleen Meert; Jerry Zimmerman; Christopher Newth; Rick Harrison; Douglas F Willson; Carol Nicholson
Journal:  Pediatr Crit Care Med       Date:  2009-07       Impact factor: 3.624
  7 in total

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