Literature DB >> 11021805

T-Independent immune response: new aspects of B cell biology.

S Fagarasan1, T Honjo.   

Abstract

Recent results emphasize the roles of T-independent antibody response in humoral defenses, for which B1 cells and marginal zone B cells are mostly responsible. We discuss how these cells are activated, migrate, and differentiate into antibody-producing cells in various lymphoid tissues. Based on recent findings in each of these areas of B cell biology, we propose a possible mechanism for peripheral tolerance of autoreactive B cells at target organs.

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Year:  2000        PMID： 11021805     DOI： 10.1126/science.290.5489.89

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  123 in total

Review 1.  Naive and memory B cells in T-cell-dependent and T-independent responses.

Authors:  R H Zubler
Journal:  Springer Semin Immunopathol       Date:  2001-12

Review 2.  T lymphocyte dependence of the antibody response to 'T lymphocyte independent type 2' antigens.

Authors:  A Jeurissen; J L Ceuppens; X Bossuyt
Journal:  Immunology       Date:  2004-01       Impact factor: 7.397

3.  After chemotherapy, functional humoral response capacity is restored before complete restoration of lymphoid compartments.

Authors:  A Zandvoort; M E Lodewijk; P A Klok; M A Breukels; G T Rijkers; W Timens
Journal:  Clin Exp Immunol       Date:  2003-01       Impact factor: 4.330

4.  DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL.

Authors:  Mikhail B Litinskiy; Bernardetta Nardelli; David M Hilbert; Bing He; Andras Schaffer; Paolo Casali; Andrea Cerutti
Journal:  Nat Immunol       Date:  2002-08-05       Impact factor: 25.606

Review 5.  Mucosal immunity: overcoming the barrier for induction of proximal responses.

Authors:  Brent S McKenzie; Jamie L Brady; Andrew M Lew
Journal:  Immunol Res       Date:  2004       Impact factor: 2.829

6.  Cannabinoid receptor 2 is critical for the homing and retention of marginal zone B lineage cells and for efficient T-independent immune responses.

Authors:  Sreemanti Basu; Avijit Ray; Bonnie N Dittel
Journal:  J Immunol       Date:  2011-11-02       Impact factor: 5.422

7.  Pivotal advance: peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4+ T cells.

Authors:  David Parra; Aja M Rieger; Jun Li; Yong-An Zhang; Louise M Randall; Christopher A Hunter; Daniel R Barreda; J Oriol Sunyer
Journal:  J Leukoc Biol       Date:  2011-11-04       Impact factor: 4.962

8.  B1a lymphocytes in the rectal mucosa of ulcerative colitis patients.

Authors:  Lino Polese; Riccardo Boetto; Giuseppe De Franchis; Imerio Angriman; Andrea Porzionato; Lorenzo Norberto; Giacomo Carlo Sturniolo; Veronica Macchi; Raffaele De Caro; Stefano Merigliano
Journal:  World J Gastroenterol       Date:  2012-01-14       Impact factor: 5.742

9.  Vitamin A-dependent transcriptional activation of the nuclear factor of activated T cells c1 (NFATc1) is critical for the development and survival of B1 cells.

Authors:  Mikako Maruya; Keiichiro Suzuki; Hanae Fujimoto; Michio Miyajima; Osami Kanagawa; Teruhiko Wakayama; Sidonia Fagarasan
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-27       Impact factor: 11.205

Review 10.  Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase.

Authors:  W N Khan
Journal:  Immunol Res       Date:  2001       Impact factor: 2.829
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