Literature DB >> 10998617

Macromolecular structure determination by cryo-electron microscopy.

H R Saibil1.   

Abstract

Recent advances in transmission electron microscopy (EM) hardware, low-temperature methods and image-processing software have made cryo-EM an important complement to X-ray crystallography and NMR for macromolecular structure determination, particularly of large assemblies. This review provides a summary of the main advances and a survey of the capabilities of this approach.

Mesh：

Year:  2000        PMID： 10998617     DOI： 10.1107/s0907444900010787

Source DB:  PubMed          Journal:  Acta Crystallogr D Biol Crystallogr        ISSN： 0907-4449


  16 in total

Review 1.  Structure and function of efflux pumps that confer resistance to drugs.

Authors:  M Ines Borges-Walmsley; Kenneth S McKeegan; Adrian R Walmsley
Journal:  Biochem J       Date:  2003-12-01       Impact factor: 3.857

Review 2.  Nanotools for megaproblems: probing protein misfolding diseases using nanomedicine modus operandi.

Authors:  Vladimir N Uversky; Alexander V Kabanov; Yuri L Lyubchenko
Journal:  J Proteome Res       Date:  2006-10       Impact factor: 4.466

3.  Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics.

Authors:  Leonardo G Trabuco; Elizabeth Villa; Kakoli Mitra; Joachim Frank; Klaus Schulten
Journal:  Structure       Date:  2008-05       Impact factor: 5.006

Review 4.  On the relevance of defining protein structures in cancer research.

Authors:  Inés G Muñoz; Franciso J Blanco; Guillermo Montoya
Journal:  Clin Transl Oncol       Date:  2008-04       Impact factor: 3.405

Review 5.  Diffraction Techniques in Structural Biology.

Authors:  Martin Egli
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2016-06-01

6.  Diffraction techniques in structural biology.

Authors:  Martin Egli
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2010-06

Review 7.  Discovery through the computational microscope.

Authors:  Eric H Lee; Jen Hsin; Marcos Sotomayor; Gemma Comellas; Klaus Schulten
Journal:  Structure       Date:  2009-10-14       Impact factor: 5.006

Review 8.  Crystal structures of fusion proteins with large-affinity tags.

Authors:  Douglas R Smyth; Marek K Mrozkiewicz; William J McGrath; Pawel Listwan; Bostjan Kobe
Journal:  Protein Sci       Date:  2003-07       Impact factor: 6.725

9.  Bayesian analysis of individual electron microscopy images: towards structures of dynamic and heterogeneous biomolecular assemblies.

Authors:  Pilar Cossio; Gerhard Hummer
Journal:  J Struct Biol       Date:  2013-10-24       Impact factor: 2.867

Review 10.  Structural analysis of macromolecular assemblies by electron microscopy.

Authors:  E V Orlova; H R Saibil
Journal:  Chem Rev       Date:  2011-09-16       Impact factor: 60.622
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