Literature DB >> 10991886

Bioavailability of praziquantel increases with concomitant administration of food.

N Castro1, R Medina, J Sotelo, H Jung.   

Abstract

In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

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Year:  2000        PMID： 10991886      PMCID： PMC90177          DOI： 10.1128/AAC.44.10.2903-2904.2000

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Dietary fat level and short-term effects of a high-fat meal on food intake and metabolism.

Authors:  C J Silberbauer; B Jacober; W Langhans
Journal:  Ann Nutr Metab       Date:  1998       Impact factor: 3.374

2.  Pharmacokinetic study of praziquantel administered alone and in combination with cimetidine in a single-day therapeutic regimen.

Authors:  H Jung; R Medina; N Castro; T Corona; J Sotelo
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

3.  Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis.

Authors:  L S Olanoff; T Walle; T D Cowart; U K Walle; M J Oexmann; E C Conradi
Journal:  Clin Pharmacol Ther       Date:  1986-10       Impact factor: 6.875

4.  Sensitive high-performance liquid chromatographic assay for praziquantel in plasma, urine and liver homogenates.

Authors:  D F González-Esquivel; C M Okuno; M Sánchez Rodríguez; J Solelo Morales; H J Cook
Journal:  J Chromatogr       Date:  1993-03-05

5.  Pharmacokinetic interaction between praziquantel and albendazole in Sudanese men.

Authors:  M Homeida; W Leahy; S Copeland; M M Ali; D W Harron
Journal:  Ann Trop Med Parasitol       Date:  1994-10

6.  Effect of food on hepatic blood flow: implications in the "food effect" phenomenon.

Authors:  C K Svensson; D J Edwards; P M Mauriello; S H Barde; A C Foster; R A Lanc; E Middleton; D Lalka
Journal:  Clin Pharmacol Ther       Date:  1983-09       Impact factor: 6.875

7.  Statistical moments in pharmacokinetics.

Authors:  K Yamaoka; T Nakagawa; T Uno
Journal:  J Pharmacokinet Biopharm       Date:  1978-12

8.  Pharmacokinetics of praziquantel in healthy volunteers and patients with schistosomiasis.

Authors:  M E Mandour; H el Turabi; M M Homeida; T el Sadig; H M Ali; J L Bennett; W J Leahey; D W Harron
Journal:  Trans R Soc Trop Med Hyg       Date:  1990 May-Jun       Impact factor: 2.184

9.  Plasma levels of praziquantel decrease when dexamethasone is given simultaneously.

Authors:  M L Vazquez; H Jung; J Sotelo
Journal:  Neurology       Date:  1987-09       Impact factor: 9.910

10.  Effect of carbohydrates on estimated hepatic blood flow.

Authors:  C K Svensson; P M Mauriello; S H Barde; E Middleton; D Lalka
Journal:  Clin Pharmacol Ther       Date:  1984-05       Impact factor: 6.875
  10 in total
  21 in total

1.  Interaction between grapefruit juice and praziquantel in humans.

Authors:  Nelly Castro; Helgi Jung; Roberto Medina; Dinora González-Esquivel; Mario Lopez; Julio Sotelo
Journal:  Antimicrob Agents Chemother       Date:  2002-05       Impact factor: 5.191

Review 2.  Combination chemotherapy of schistosomiasis in laboratory studies and clinical trials.

Authors:  Jürg Utzinger; Jennifer Keiser; Xiao Shuhua; Marcel Tanner; Burton H Singer
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

Review 3.  Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.

Authors:  Nuno Vale; Maria João Gouveia; Gabriel Rinaldi; Paul J Brindley; Fátima Gärtner; José M Correia da Costa
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

Review 4.  A Review of Food-Drug Interactions on Oral Drug Absorption.

Authors:  Jianyuan Deng; Xiao Zhu; Zongmeng Chen; Chun Ho Fan; Him Shek Kwan; Chi Ho Wong; Ka Yi Shek; Zhong Zuo; Tai Ning Lam
Journal:  Drugs       Date:  2017-11       Impact factor: 9.546

5.  Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis.

Authors:  Hector H Garcia; Andres G Lescano; Vera L Lanchote; E Javier Pretell; Isidro Gonzales; Javier A Bustos; Osvaldo M Takayanagui; Pierina S Bonato; John Horton; Herbert Saavedra; Armando E Gonzalez; Robert H Gilman
Journal:  Br J Clin Pharmacol       Date:  2011-07       Impact factor: 4.335

6.  R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini.

Authors:  Christine Falcoz; Serge Guzy; Jana Kovač; Isabel Meister; Jean Coulibaly; Somphou Sayasone; David Wesche; Yu-Wei Lin; Jennifer Keiser
Journal:  J Pharmacokinet Pharmacodyn       Date:  2022-01-13       Impact factor: 2.745

7.  Effects of food on the relative bioavailability of lapatinib in cancer patients.

Authors:  Kevin M Koch; Nandi J Reddy; Roger B Cohen; Nancy L Lewis; Bonnie Whitehead; Kathleen Mackay; Andrew Stead; Andrew P Beelen; Lionel D Lewis
Journal:  J Clin Oncol       Date:  2009-02-02       Impact factor: 44.544

8.  Pharmacokinetics of Praziquantel in Schistosoma mansoni- and Schistosoma haematobium-Infected School- and Preschool-Aged Children.

Authors:  Jana Kovač; Isabel Meister; Anna Neodo; Gordana Panic; Jean T Coulibaly; Christine Falcoz; Jennifer Keiser
Journal:  Antimicrob Agents Chemother       Date:  2018-07-27       Impact factor: 5.191

9.  Cysticidal Efficacy of Combined Treatment With Praziquantel and Albendazole for Parenchymal Brain Cysticercosis.

Authors:  Hector H Garcia; Andres G Lescano; Isidro Gonzales; Javier A Bustos; E Javier Pretell; John Horton; Herbert Saavedra; Armando E Gonzalez; Robert H Gilman
Journal:  Clin Infect Dis       Date:  2016-03-16       Impact factor: 9.079

10.  Efficacy of praziquantel against Schistosoma mekongi and Opisthorchis viverrini: a randomized, single-blinded dose-comparison trial.

Authors:  Leonore Lovis; Tippi K Mak; Khampheng Phongluxa; Phonepasong Ayé Soukhathammavong; Youthanavanh Vonghachack; Jennifer Keiser; Penelope Vounatsou; Marcel Tanner; Christoph Hatz; Jürg Utzinger; Peter Odermatt; Kongsap Akkhavong
Journal:  PLoS Negl Trop Dis       Date:  2012-07-24
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