Literature DB >> 11959616

Interaction between grapefruit juice and praziquantel in humans.

Nelly Castro1, Helgi Jung, Roberto Medina, Dinora González-Esquivel, Mario Lopez, Julio Sotelo.   

Abstract

After a single oral dose of praziquantel with 250 ml of grapefruit juice, the area under the concentration-time curve and the maximum concentration in plasma of praziquantel (Cmax) were significantly increased (Cmax for water treatment, 637.71 +/- 128.5 ng/ml; and Cmax for grapefruit juice treatment, 1,037.65 +/- 305.7 ng/ml, P < 0.05). No statistically significant differences were found in the time to maximum concentration of drug in plasma or elimination half-life.

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Year:  2002        PMID： 11959616      PMCID： PMC127135          DOI： 10.1128/AAC.46.5.1614-1616.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Bioavailability of praziquantel increases with concomitant administration of food.

Authors:  N Castro; R Medina; J Sotelo; H Jung
Journal:  Antimicrob Agents Chemother       Date:  2000-10       Impact factor: 5.191

2.  Influence of grapefruit juice on cisapride pharmacokinetics.

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Journal:  Clin Pharmacol Ther       Date:  1999-04       Impact factor: 6.875

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Authors:  D G Bailey; J D Spence; C Munoz; J M Arnold
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Review 4.  Grapefruit juice and drugs. How significant is the interaction?

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5.  Therapy of parenchymal brain cysticercosis with praziquantel.

Authors:  J Sotelo; F Escobedo; J Rodriguez-Carbajal; B Torres; F Rubio-Donnadieu
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6.  Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics.

Authors:  D G Bailey; J M Arnold; H A Strong; C Munoz; J D Spence
Journal:  Clin Pharmacol Ther       Date:  1993-12       Impact factor: 6.875

7.  Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans.

Authors:  P A Soons; B A Vogels; M C Roosemalen; H C Schoemaker; E Uchida; B Edgar; J Lundahl; A F Cohen; D D Breimer
Journal:  Clin Pharmacol Ther       Date:  1991-10       Impact factor: 6.875

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Authors:  O H Del Brutto; J Sotelo; G C Roman
Journal:  Clin Infect Dis       Date:  1993-10       Impact factor: 9.079

9.  Characterisation of praziquantel metabolism by rat liver microsomes using cytochrome P450 inhibitors.

Authors:  C M Masimirembwa; J A Hasler
Journal:  Biochem Pharmacol       Date:  1994-11-01       Impact factor: 5.858

10.  Interaction between grapefruit juice and midazolam in humans.

Authors:  H H Kupferschmidt; H R Ha; W H Ziegler; P J Meier; S Krähenbühl
Journal:  Clin Pharmacol Ther       Date:  1995-07       Impact factor: 6.875
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Journal:  Drugs       Date:  2010-12-24       Impact factor: 9.546

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6.  In vitro and in vivo human metabolism and pharmacokinetics of S- and R-praziquantel.

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7.  Clinically relevant enantiomer specific R- and S-praziquantel pharmacokinetic drug-drug interactions with efavirenz and ritonavir.

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Review 8.  Medicinal importance of grapefruit juice and its interaction with various drugs.

Authors:  Jawad Kiani; Sardar Z Imam
Journal:  Nutr J       Date:  2007-10-30       Impact factor: 3.271

9.  Pharmacokinetic parameters of ifosfamide in mouse pre-administered with grapefruit juice or naringin.

Authors:  Eduardo Madrigal-Bujaidar; Edilberto Pérez-Montoya; Sandra García-Medina; José Melesio Cristóbal-Luna; José A Morales-González; Eduardo Osiris Madrigal-Santillán; Rogelio Paniagua-Pérez; Isela Álvarez-González
Journal:  Sci Rep       Date:  2019-11-12       Impact factor: 4.379
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