Literature DB >> 10990416

A new route to spirooxindoles.

S T Hilton1, T C Ho, G Pljevaljcic, K Jones.   

Abstract

[reaction: see text]Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10990416     DOI： 10.1021/ol0061642

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  14 in total

1.  5-(4-Fluoro-benzyl-idene)-4'-(4-fluoro-phen-yl)-1,1'-dimethyl-dispiro-[piperidine-3,3'-pyrrolidine-2',3''-indoline]-4,2''-dione.

Authors:  V Rajni Swamy; S Ramaswamy; N Srinivasan; R Ranjith Kumar; R V Krishnakumar
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-09-05

2.  Chemistry of withaferin-A: chemo, regio, and stereoselective synthesis of novel spiro-pyrrolizidino-oxindole adducts of withaferin-A via one-pot three-component [3+2] azomethine ylide cycloaddition and their cytotoxicity evaluation.

Authors:  Yogesh P Bharitkar; Satish Kanhar; Neradibilli Suneel; Susanta Kumar Mondal; Abhijit Hazra; Nirup B Mondal
Journal:  Mol Divers       Date:  2015-03-08       Impact factor: 2.943

3.  5,6-Dimeth-oxy-4',5'-diphenyl-indane-2-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-1,2''-dione.

Authors:  Mohamed Ashraf Ali; Rusli Ismail; Soo Choon Tan; Chin Sing Yeap; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-11

4.  1-Benzyl-4',5'-diphenyl-piperidine-3-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-4,2''-dione.

Authors:  J Suresh; R Suresh Kumar; A Rajapriya; S Perumal; P L Nilantha Lakshman
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-12-17

5.  A green, multicomponent, regio- and stereo-selective 1,3-dipolar cycloaddition of azides and azomethine ylides generated in situ with bifunctional dipolarophiles using PEG-400.

Authors:  Jayant Sindhu; Harjinder Singh; J M Khurana
Journal:  Mol Divers       Date:  2014-02-28       Impact factor: 2.943

6.  Synthesis of novel steroidal 16-spiroisoxazolines by 1,3-dipolar cycloaddition, and an evaluation of their antiproliferative activities in vitro.

Authors:  Éva Frank; Dóra Kovács; Gyula Schneider; János Wölfling; Tibor Bartók; István Zupkó
Journal:  Mol Divers       Date:  2014-04-02       Impact factor: 2.943

7.  Synthesis and crystal structures of 5'-phenylspiro[indoline-3, 2'-pyrrolidin]-2-one derivatives.

Authors:  Jeyaperumal Kalyana Sundar; Stephen Michael Rajesh; Jeyaraman Sivamani; Subbu Perumal; Subramanian Natarajan
Journal:  Chem Cent J       Date:  2011-07-26       Impact factor: 4.215

8.  1'-Methyl-4'-phenyl-2''-sulfanylidene-dispiro-[indoline-3,2'-pyrrolidine-3',5''-1,3-thia-zolidine]-2,4''-dione.

Authors:  Sampath Natarajan; Rita Mathews
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-01-11

9.  Methyl 3'-benzyl-4'-(2,4-di-chloro-phen-yl)-1'-methyl-2-oxo-spiro-[indoline-3,2'-pyrrolidine]-3'-carboxyl-ate.

Authors:  S Karthikeyan; P Narayanan; K Sethusankar; Anthonisamy Devaraj; Manickam Bakthadoss
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-02-22

10.  Methyl 4'-(3-bromo-phen-yl)-3'-(2,5-di-methyl-benz-yl)-1'-methyl-2-oxo-spiro-[indo-line-3,2'-pyrrolidine]-3'-carboxyl-ate.

Authors:  S Karthikeyan; K Sethusankar; Anthonisamy Devaraj; Manickam Bakthadoss
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-02-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.